Browsing by Author "Bruno, Ines"
Now showing items 1-4 of 4
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Design and structural optimization of new molecules as potential antiinflammatory and/or anticancer agents.
Strocchia, Maria (Universita degli studi di Salerno, 2015-03-10)L’infiammazione ed il cancro sono due complessi meccanismi patologici in cui risultano coinvolti una serie di differenti mediatori molecolari. La profonda connessione tra cancro ed infiammazione è ben nota e la modulazione ... -
Design, synthesis and biological activity of new target selective antitumoral agents
Russo, Alessandra (Universita degli studi di Salerno, 2018-04-05)Cancer development is a complex pathological process that exploits a variety of biological actors. The identification of new molecular entities able to interfere with new biological targets, involved in tumorigenesis, is ... -
Design, synthesis and biological evaluation of small molecules able to interact with macromolecular targets involved in tumor pathology
Ruggiero, Dafne (Universita degli studi di Salerno, 2021-05-06)Inflammation and cancer are two complex pathological processes that exploit several molecular actors. The identification of new platforms able to interfere with biological targets placed at the crossroads of these two ... -
Design, synthesis and pharmacological studies of structural analogues modeled on bioactive natural products
De Simone, Rosa (Universita degli studi di Salerno, 2011-03-21)Microsomal prostaglandin E2 synthase-1 (mPGES-1) is the enzyme responsible for the conversion of the cyclooxygenase (COX)-derived prostaglandins (PG)H2 into PGE2. This enzyme is deeply involved in different pathologies; ...