Browsing by Author "De Simone, Rosa"
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Design, synthesis and pharmacological studies of structural analogues modeled on bioactive natural products
De Simone, Rosa (Universita degli studi di Salerno, 2011-03-21)Microsomal prostaglandin E2 synthase-1 (mPGES-1) is the enzyme responsible for the conversion of the cyclooxygenase (COX)-derived prostaglandins (PG)H2 into PGE2. This enzyme is deeply involved in different pathologies; ...