Browsing by Author "Finelli, Rosa"
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Larger blood pressure reduction by fixed-dose compared to free dose combination therapy of ace inhibitor and calcium antagonist in hypertensive patients
Visco, Valeria; Finelli, Rosa; Pascale, Antonietta Valeria; Giannotti, Rocco; Fabbricatore, Davide; Ragosa, Nicola; Ciccarelli, Michele; Iaccarino, Guido (2017)The introduction of fixed combination of ACEi+CCB (Fixed) has significantly increased patients compliance and adherence to therapy. At the moment, however, there are no data suggesting the better control of once-daily ... -
A polymorphism within the promoter of the dopamine receptor D1 (DRD1 -48A7G) associates with impaired kidney function in white hypertensive patients
Cipolletta, Ersilia; Ciccarelli, Michele; Izzo, Raffaele; Finelli, Rosa; Trimarco, Bruno; Iaccarino, Guido (2012)Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension ... -
To NFkB or not to NFkB: the dilemma on how to inhibit a cancer cell fate regulator
Sorriento, Daniela; Illario, Maddalena; Finelli, Rosa; Iaccarino, Guido (2012)Nuclear factor B (NFB) is a transcription factor that plays an important role in carcinogenesis as well as in the regulation of inflammatory response. NFB is constitutively expressed in tumours where it induces ...