Sfoglia per Autore "Iaccarino, Guido"

Items 1-17 di 17

    • Adrenergic mechanism in the control of endothelial function 

      Sorriento, Daniela; Trimarco, Bruno; Iaccarino, Guido (2011)
      There is considerable evidence that many disease are associated with endothelial dysfunction and reduced nitric oxide production such as hypertension, obesity, dyslipidemias, diabetes, heart failure, atherosclerosis. Notably ...

    • An approach to prevent frailty in community dwelling older adults: a pilot study performed in Campania region in the framework of the PERSSILAA project 

      Cataldi, Mauro; De Luca, Vincenzo; Tramontano, Giovanni; Del Giudice, Carmine; Grimaldi, Iolanda; Cuccaro, Paula; Speranza, Patrizia; Iadicicco, Giuseppe; Iadicicco, Vincenzo; Carotenuto, Felicia; Riccio, Paolo A.; Di Spigna, Gaetano; Renzullo, Andrea; Vuolo, Laura; Barrea, Luigi; Savastano, Silvia; Colao, Annaria; Liotta, Giuseppe; Iaccarino, Guido; Abete, Pasquale; Buono, Pasqualina; Vollenbroek-Hutten, Miriam; Illario, Maddalena (2019)
      We developed and tested an innovative physical training method in older adults that embeds the gym program into everyday life in the most conservative way possible. Physical training was included in the activities of ...

    • Dual role of grk5 in cancer development and progression 

      Gambardella, Jessica; Franco, Antonietta; Del Giudice, Carmine; Fiordelisi, Antonella; Cipolletta, Ersilia; Ciccarelli, Michele; Trimarco, Bruno; Iaccarino, Guido; Sorriento, Daniela (2016)
      GRK5 is a multifunctional protein that is able to move within the cell in response to various stimuli to regulate key intracellular signaling from receptor activation, on plasmamembrane, to gene transcription, in the ...

    • Editorial: Multi-actor collaboration in healthcare to address the emerging health needs of an aging population 

      Illario, Maddalena; Coscioni, Enrico; De Luca, Vincenzo; Cataldi, Mauro; Postiglione, Alfredo; Iaccarino, Guido (2019)

    • Implementing an ict-based polypharmacy management program in Italy 

      Arcopinto, Michele; Cataldi, Mauro; De Luca, Vincenzo; Orlando, Valentina; Simeone, Giuseppe; D’Assante, Roberta; Postiglione, Alfredo; Guida, Antonella; Trama, Ugo; Illario, Maddalena; Coscioni, Enrico; Iaccarino, Guido; Cuccaro, Paula; D’Onofrio, Gaetano; Vigorito, Carlo; Cittadini, Antonio; Ferrara, Nicola; Menditto, Enrico (2017)
      Although there is evidence of a growing awareness of the problem, no official policy statements or regulatory guidelines on polypharmacy have been released up to date by Italian Health Authorities. Medication review, ...

    • Innovative approaches to active and healthy ageing: Campania experience to improve the adoption of innovative good practices 

      De Luca, Vincenzo; Tramontano, Giovanni; Del Giudice, Carmine; Grimaldi, Iolanda; Romano, Rosaria; Liguori, Ilaria; Carpinelli Mazzi, Michele; Di Carluccio, Nadia; Riccio, Paolo A.; Speranza, Patrizia; Iavarone, Alessandro; Abete, Pasquale; Postiglione, Amedeo; Cataldi, Mauro; Vallone, Cayetano; Giallauria, Francesco; Cittadini, Antonio; Triggiani, Maurizio; Savastano, Silvia; Menditto, Enrica; Leonardini, Lisa; Colao, Annaria; Triassi, Maria; Iaccarino, Guido; Postiglione, Amedeo; Coscioni, Enrico; Illario, Maddalena (2019)
      The demographic projections on the European population predict that people aged over 60 will increase by about two million/year in the next decades. Since 2012, the Campania Reference Site of the European Innovation ...

    • Larger blood pressure reduction by fixed-dose compared to free dose combination therapy of ace inhibitor and calcium antagonist in hypertensive patients 

      Visco, Valeria; Finelli, Rosa; Pascale, Antonietta Valeria; Giannotti, Rocco; Fabbricatore, Davide; Ragosa, Nicola; Ciccarelli, Michele; Iaccarino, Guido (2017)
      The introduction of fixed combination of ACEi+CCB (Fixed) has significantly increased patients compliance and adherence to therapy. At the moment, however, there are no data suggesting the better control of once-daily ...

    • Models for preclinical studies in aging-related disorders: one is not for all 

      Santulli, Gaetano; Borras, Consuelo; Bousquet, Jean; Calzà, Laura; Cano, Antonio; Illario, Maddalena; Franceschi, Claudio; Liotta, Giuseppe; Maggio, Marcello; Molloy, William D.; Montuori, Nunzia; O’Caoimh, Rónán; Orfila, Francesco; Rauter, Amelia P.; Santoro, Aurelia; Iaccarino, Guido (2015)
      Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment–effect relationships to human subjects. ...

    • A polymorphism within the promoter of the dopamine receptor D1 (DRD1 -48A7G) associates with impaired kidney function in white hypertensive patients 

      Cipolletta, Ersilia; Ciccarelli, Michele; Izzo, Raffaele; Finelli, Rosa; Trimarco, Bruno; Iaccarino, Guido (2012)
      Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension ...

    • Proceedings of the eip on aha: a3 action group on frailty 

      Illario, Maddalena; Iaccarino, Guido; Piazza, Ornella; Menditto, Erica (2015)

    • Public prevention plans to manage climate change and respiratory allergic diseases. Innovative models used in Campania Region (Italy): the twinning Aria implementation and the allergy safe tree: decalogue 

      Patella, Vincenzo; Florio, Giovanni; Magliacane, Diomira; Giuliano, Ada; Russo, Laura Filomena; D’Amato, Valeria; De Luca, Vincenzo; Iaccarino, Guido; Illario, Maddalena; Bousquet, Jean (2019)
      In recent years, climate change has been influenced by air pollution, and this destructive combination has justifiably sounded an alarm for nations and many institutional bodies worldwide. Official reports state that ...

    • Rays sting: the acute cellular effects of ionizing radiation exposure 

      Franco, Antonietta; Ciccarelli, Michele; Sorriento, Daniela; Napolitano, Luigi; Fiordelisi, Antonella; Trimarco, Bruno; Durante, Marco; Iaccarino, Guido (2016)
      High-precision radiation therapy is a clinical approach that uses the targeted delivery of ionizing radiation, and the subsequent formation of reactive oxygen species (ROS) in high proliferative, radiation sensitive cancers. ...

    • Redesigning Service Delivery for Hypertensive Patients: A Methodological Guideline to Improve the Management of Chronic Diseases 

      Ippolito, Adelaide; Cannavacciuolo, Lorella; Ponsiglione, Cristina; De Luca, Nicola; Iaccarino, Guido; Illario, Maddalena (2014)
      Best care is not necessarily the most expensive, but the most appropriate, and prevention is the most powerful tool to promote health. A novel approach might envision the reduction of hospital admittance (thus meeting a ...

    • The european innovation partnership on active and healthy ageing synergies: protocol for a prospective observational study to measure the impact of a community-based program on prevention and mitigation of frailty (ICP –PMF) in community-dwelling older adults 

      Liotta, Giuseppe; Orfila, Francesc; Vollenbroek-Hutten, Miriam; Roller-Winsbergerm, Regina; Musian, Daniele; Alvino, Sam; O'Caoimh, Ronan; Cano, Antonio; Molloy, William; Iaccarino, Guido; Marazzi, Maria Cristina; Inzerilli, Maria Chiara; Madaro, Olga; Paúl, Constança; Csonka, Peter; Menditto, Enrica; Maggio, Maria; Scarcella, Paola; Gilardi, Fabrizio; Lucaroni, Francesca; Abete, Pasquale; Girardi, Viviane; Barra, Rita; Palombi, Leonardo (2016)
      Aim of this paper is to describe the protocol of the study “Impact of a Community-based Program on Prevention and Mitigation of Frailty in communitydwelling older adults” developed in the framework of the European ...

    • The reference site collaborative network of the european innovation partnership on active and healthy ageing 

      Bousquet, Jean; Ilario, Maddalena; Farrell, John; Batey, Nick; Carriazo, Ana M.; Malva, João; Hajjam, Jawad; Colgan, Elaine; Guldemond, Nick; Perälä-Heape, Maritta; Onorato, Gabrielle L.; Bedbrook, Anna; Leonardini, Lisa; Stroetman, Veli; Birov, Strahil; Abreu, Cidalina; Abrunhosa, Ana; Agrimi, Adriana; Alalääkkölä, Timo; Allegretti, Nikša; Alonso-Trujillo, Federico; Álvarez-Benito, Marina; Angioli, Serena; Apóstolo, João; Armitage, Geoffrey; Arnavielhe, Sylvie; Baena-Parejo, Maria Isabel; Bamidis, Panagiotis; Balenović, Antonija; Barbolini, Mirka; Baroni, Irene; Blain, Hubert; Bernard, Pierrick L.; Bersani, Maurizio; Berti, Enrico; Bogatyrchuk, Leonid; Bourret, Richard; Brehm, Jörg; Brussino, Luisa; Buhr, Daniel; Bultje, Daan; Cabeza, Elena; Cano, Antonio; De Capitani, Cristina; Carantoña, Elena; Cardoso, Anabela; Coll Clavero, Juan I.; Combe, Bernard; Conforti, Diego; Coppola, Liliana; Corti, Fiorenzo; Coscioni, Enrico; Costa, Elisio; Crooks, Gregory; Cunha, Antônio; Daien, Claire; Dantas, Carina; Darpón Sierra, Jon; Davoli, Marina; Dedeu Baraldes, Antoni; De Luca, Vincenzo; De Nardi, Livio; Di Ciano, Marco; Dozet, Alexander; Ekinci, Bilge; Erve, Sylvie; Espinoza Almendro, Juan Manuel; Fait, Antonella; Fensli, Rune; Fernandez Nocelo, Susana; Gálvez-Daza, Purificación; Gámez-Payá, Javier; García Sáez, Mercedes; Garcia Sanchez, Inés; Gemicioğlu, Bilun; Goetzke, Wolfgang; Goossens, Edwig; Geurden, Marleen; Gütter, Zdeněk; Hansen, Harry; Hartman, Sanna; Hegendörfer, Gerhard; Heikka, Helena; Henderson, Donna; Héran, Daphné; Hirvonen, Susanna; Iaccarino, Guido; Jansson, Noora; Kallasvaara, Heikki; Kalyoncu, Ali Fuat; Kirchmayer, Ursula; Kokko, Jaana A.; Korpelainen, Juha; Kostka, Tomasz; Kuna, Piotr; Lajarín Ortega, Teresa; Lama, Carmen M.; Laune, Daniel; Lauri, Davide; Ledroit, Valentin; Levato, Gabriella; Lewis, Leo; Liotta, Giovanni; Lundgren, Lilian; Lupiañez-Villanueva, Francisco; Mc Garry, Paul; Maggio, Marcello; Manuel de Keenoy, Esteban; Martinez, C.; Martínez - Domene, Manuel; Martínez-Lozano Aranaga, Beatriz; Massimilliano, Mahnic; Maurizio, A.; Mayora, Oscar; Melle, Christian; Mendez-Zorilla, Amaia; Mengon, H.; Mercier, Grégoire; Mercier, Jacques; Meyer, Ingo; Millet Pi-Figueras, Alejandra; Mitsias, Panayiotis; Molloy, David W.; Monti, Riccardo; Moro, Maria Luisa; Muranko, H.; Nalin, Marco; Nobili, Alessandro; Noguès, Marc; O’Caoimh, Rónán; Pais, Sandra; Papini, Donato; Parkkila, Pettery; Pattichis, Constantinos; Pavlickova, Andrea; Peiponen, Arja; Pereira, Susana; Pépin, Jean Louis; Piera Jiménez, Jordi; Portheine, Peter; Potel, Louis; Pozzi, Anna Carla; Quiñonez, Pablo; Ramirez Lauritsen, Xenia; Ramos, Maria João; Rännäli-Kontturi, Anne; Risino, Amanda; Robalo-Cordeiro, Carlos; Rolla, Giancarlo; Roller, Regina; Romano, Maria; Romano, Virginia; Ruiz-Fernández, Jesús; Saccavini, Claudio; Sachinopoulou, Anna; Sánchez Rubio, Maria José; Santos, Lucia; Scalvini, Sheila; Scopetani, Elisa; Smedberg, Daniel; Solana-Lara, Rafael; Sołtysik, Bartlomiej; Sorlini, Marzio; Stericker, Stephen; Stramba Badiale, Marco; Taillieu, Inge; Tervahauta, Markku; Teixeira, Ana; Tikanmäki, Heidi; Todo-Bom, Ana; Tooley, André; Tuulonen, Anja; Tziraki, Chariklia; Ussai, Silvia; Van der Veen, Sabina; Venchiarutti, Arrigo; Verdoy-Berastegi, Dolores; Verissimo, Manuel; Visconti, Laura; Vollenbroek-Hutten, Miriam; Weinzerl, Katharina; Wozniak, Lucyna; Yorgancıoğlu, Arzu; Zavagli, Veronica; Zurkuhlen, Alexia J. (2019)
      Seventy four Reference Sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) have been recognised by the European Commission in 2016 for their commitment to excellence in investing ...

    • To NFkB or not to NFkB: the dilemma on how to inhibit a cancer cell fate regulator 

      Sorriento, Daniela; Illario, Maddalena; Finelli, Rosa; Iaccarino, Guido (2012)
      Nuclear factor B (NFB) is a transcription factor that plays an important role in carcinogenesis as well as in the regulation of inflammatory response. NFB is constitutively expressed in tumours where it induces ...

    • Trafficking GRK2: Cellular and Metabolic consequences of GRK2 subcellular localization 

      Sorriento, Daniela; Ciccarelli, Michele; Santulli, Gaetano; Illario, Maddalena; Trimarco, Bruno; Iaccarino, Guido (2014)
      G protein coupled receptor kinase 2 (GRK2) has a key role in cellular function by regulating different intracellular mechanisms in a kinase dependent or independent manner. In this review we have dealt with the recently ...