http://elea.unisa.it/xmlui/handle/10556/751 Mon, 20 Apr 2026 12:20:11 GMT 2026-04-20T12:20:11Z http://elea.unisa.it/xmlui/handle/10556/867 A “broken heart” syndrome case after cesarean delivery. prevention and risk assessment Petta, Raffaele; Zullo, Fulvio; Tipaldi, A.; Guida, Maurizio Tue, 01 Jan 2013 00:00:00 GMT http://elea.unisa.it/xmlui/handle/10556/867 2013-01-01T00:00:00Z http://elea.unisa.it/xmlui/handle/10556/866 Use of equine pericardium sheet (lyomesh®) as dura mater substitute in endoscopic endonasal transsphenoidal surgery Cavallo, Luigi M.; Solari, Domenico; Somma, Teresa; Di Somma, Alberto; Chiaramonte, Carmela; Cappabianca, Paolo Objective: The aim of this study was to describe the use of equine pericardium sheet (Lyomesh®) as dural substitute for sellar reconstruction after endoscopic endonasal transsphenoidal surgery for the removal of pituitary adenomas. Methods: We reviewed data of patients that underwent surgery by means of an endoscopic endonasal transsphenoidal approach for the removal of pituitary adenomas over a 12-months period, starting in May 2012, i.e. when we adopted Lyomesh® (Audio Technologies, Piacenza, Italy) an equine pericardium sheet, as dura mater substitute. Results: During the 12-months period evaluated, we performed an endoscopic endonasal transsphenoidal operation for a variety of pituitary lesions on 102 consecutive patients. Among these, in 12 patients (9.4%) harboring a pituitary adenoma, the implant of the pericardium sheet was used. Four patients (33.3%) presented a small intraoperative cerebrospinal fluid (CSF) leak; in these cases the Lyomesh® was placed intradurally with fibrin glue and, thereafter, several layers were positioned in extradural space. In 8 other subjects without any evidence of CSF leak, the dural substitute was placed intradurally and fibrin glue was injected intradurally to hold the material in place. Conclusions: Even if based on a relatively small patient series, our experience demonstrated that the use of equine pericardium sheet (Lyomesh®) as dura mater substitute in transsphenoidal surgery is safe and biocompatible, as compared with other dural substitutes. Tue, 01 Jan 2013 00:00:00 GMT http://elea.unisa.it/xmlui/handle/10556/866 2013-01-01T00:00:00Z http://elea.unisa.it/xmlui/handle/10556/865 Pharmacokinetics of remifentanil: a three-compartmental modeling approach Cascone, Sara; Lamberti, Gaetano; Titomanlio, Giuseppe; Piazza, Ornella Remifentanil is a new opioid derivative drug characterized by a fast onset and by a short time of action, since it is rapidly degraded by esterases in blood and other tissues. Its pharmacokinetic and pharmacodynamics properties make remifentanil a very interesting molecule in the field of anesthesia. However a complete and versatile pharmacokinetic description of remifentanil still lacks. In this work a three-compartmental model has been developed to describe the pharmacokinetics of remifentanil both in the case in which it is administered by intravenous constant-rate infusion and by bolus injection. The model curves have been compared with experimental data published in scientific papers and the model parameters have been optimized to describe both ways of administration. The ad hoc model is adaptable and potentially useful for predictive purposes. Tue, 01 Jan 2013 00:00:00 GMT http://elea.unisa.it/xmlui/handle/10556/865 2013-01-01T00:00:00Z http://elea.unisa.it/xmlui/handle/10556/864 Perioperative anaphylactic risk score for risk-oriented premedication Manfredi, Giacomo; Pezzuto, Francesco; Balestrieri, Antonella; Lo Schiavo, Mario; Montera, Maria Carmela; Pio, Antonio; Iannelli, M.; Gargano, Domenico; Bianchi, M.J.; Casale, Giuseppe; Galimberti, Maurizio; Triggiani, Massimo; Piazza, Ornella Basing on the current knowledge, this paper is aimed to review the core characteristics of the most relevant therapeutic agents (steroids and antihistamines), administered to prevent perioperative anaphylaxis. Moreover, the Authors propose the validation of a Global Anaphylactic Risk Score, built up by recording the individual scores related to the most relevant anaphylaxis parameters (i.e. medical history, symptoms and medication for asthma, rhinitis and urticaria etc) and by adding them on all together; the score could be used in the preoperative phase to evaluate the global anaphylactic risk and to prescribe risk-oriented premedication protocols. Tue, 01 Jan 2013 00:00:00 GMT http://elea.unisa.it/xmlui/handle/10556/864 2013-01-01T00:00:00Z