Browsing Fisiopatologia, diagnostica e terapia molecolare delle malattie metaboliche by Submit Date
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The transcription factor Prep1 regulates adipose tissue functions
(Universita degli studi di Salerno, 2014-03-21)Adipose tissue is crucial for maintaining energy and metabolic homeostasis and its functionality is closely related to the adipocytes differentiation state. Adipogenesis is regulated by several transcription factors. Prep1 ... -
p53 regulates Mevalonate Metabolic pathway
(Universita degli studi di Salerno, 2014-03-14)The mevalonate pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, I provided evidences about genetic and pharmacologic perturbation of p53, which directly influenced ... -
Novel Insights into the Biological Effects of the Isoprenoid Derivative N6-Isopentenyladenosine: Involvement of the Metabolic Sensor Ampk in Angiogenesis Inhibition
(Universita degli studi di Salerno, 2014-03-19)N6-isopentenyladenosine (iPA) is a modified adenosine characterized by an isopentenyl chain derived by dimethylallyl pyrophosphate (DMAPP), an intermediate of the metabolic pathway of mevalonate, that is known to be ...
