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Redesigning Service Delivery for Hypertensive Patients: A Methodological Guideline to Improve the Management of Chronic Diseases
(2014)
Best care is not necessarily the most expensive, but the most appropriate, and prevention is the most powerful tool to promote health. A novel approach might envision the reduction of hospital admittance (thus meeting a ...
Nutrition and osteoporosis: preliminary data of campania region of european personalised ict supported service for independent living and active ageing
(2015)
Background: Bone impairment and malnutrition are associated with significant disability and mortality. PERSSILAA is an European project developing health services to detect and prevent frailty in older adults by addressing ...
Models for preclinical studies in aging-related disorders: one is not for all
(2015)
Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment–effect relationships to human subjects. ...
Sisters acts: converging signaling between CaMKII and CaMKIV, two members of the same family
(2012)
Calcium (Ca2+
) is a universal second
messenger that regulates a number of diverse cellular
processes including cell proliferation, development,
motility, secretion, learning and memory1, 2. A variety of
stimuli, ...
To NFkB or not to NFkB: the dilemma on how to inhibit a cancer cell fate regulator
(2012)
Nuclear factor B (NFB) is a transcription
factor that plays an important role in carcinogenesis as well
as in the regulation of inflammatory response. NFB is
constitutively expressed in tumours where it induces ...
The tosca registry: an ongoing, observational, multicenter registry for chronic heart failure
(2015)
The ageing of the population in western countries, the continuous increase of the prevalence of chronic diseases, the frequent coexistence of several morbid conditions (comorbidity) requires health professionals and ...
Implementing an ict-based polypharmacy management program in Italy
(2017)
Although there is evidence of a growing
awareness of the problem, no official policy statements or
regulatory guidelines on polypharmacy have been released
up to date by Italian Health Authorities. Medication
review, ...