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To be or not to be translational
Translational Research means different things to different people, but it seems crucial to almost everyone. This discipline, although defined differently in academia, regulatory institutions, and industry, shares the ...
Minimally invasive swine experimental model for the in vivo study of liver metabolism of drugs
Purpose: To develop a clinically relevant porcine model for the study of hepatic metabolism of drugs by means of hepatic vein catheterization. Materials and Methods: review of literature and elaboration of a hypothesis, ...
The use of noninvasive ventilation outside the intensive care unit: a clinical case report
Noninvasive Ventilation (NIV) is one of the best weapon at our disposal to treat respiratory failure. The early use of NIV out of the Intensive Care Unit can improve patients’ outcome. A 58-year-old man affected ...
Genetic test for dilated and hypertrophic cardiomyopathies: useful or less than useful for patients?
Genetic testing for potentially heritable cardiomyopathies has advanced from basic scientific discovery to clinical application. Nowadays, genetic diagnostic tests for cardiomyopathies are clinically available. As ...
Statistics and medicine: the indispensable know-how of the researcher
Statistics has often been misunderstood in Medicine, but it is indispensable knowledge both for the experimenter and the reader. Statistical methods allow to study diseases, patients, and epidemiological events. ...
Genetic test for the channelopaties: useful or less than useful for patients? (part 2.)
The advanced knowledge about genetic diseases and their mutations has widened the possibility to have a more precise and definitive diagnosis in many patients, but the use of genetic testing is still controversial. Actually, ...