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dc.contributor.authorMastantuono, Teresa
dc.contributor.authorDi Maro, Martina
dc.contributor.authorChiurazzi, Martina
dc.contributor.authorBattiloro, Laura
dc.contributor.authorStarita, Noemy
dc.contributor.authorNasti, Gilda
dc.contributor.authorLapi, Dominga
dc.contributor.authorIuppariello, Luigi
dc.contributor.authorCesarelli, Mario
dc.contributor.authorD’Addio, Gianni
dc.contributor.authorColantuoni, Antonio
dc.date.accessioned2020-05-22T13:10:08Z
dc.date.available2020-05-22T13:10:08Z
dc.date.issued2016
dc.identifier.citationMastantuono T, Di Maro M, Chiurazzi M, Battiloro L, Starita N, Nasti G, Lapi D, Iuppariello L, Cesarelli M,D’Addio G, Colantuoni A. Microvascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric diet. Translational Medicine @ UniSa 2016, 15(1): 1-7.it_IT
dc.identifier.issn2239-9747it_IT
dc.identifier.urihttp://www.translationalmedicine.unisa.it/indexit_IT
dc.identifier.urihttp://elea.unisa.it:8080/xmlui/handle/10556/4483
dc.identifier.urihttp://dx.doi.org/10.14273/unisa-2681
dc.description.abstractThe present study was aimed to assess the changes in skin microvascular blood flow (SBF) in newly diagnosed hyperglycemic obese subjects, administered with hypocaloric diet. Adult patients were recruited and divided in three groups: NW group (n=54), NG (n=54) and HG (n=54) groups were constituted by normal weight, normoglycemic and hyperglycemic obese subjects, respectively. SBF was measured by laser Doppler perfusion monitoring technique and oscillations in blood flow were analyzed by spectral methods under baseline conditions, at 3 and 6 months of dietary treatment. Under resting conditions, SBF was lower in HG group than in NG and NW ones. Moreover, all subjects showed blood flow oscillations with several frequency components. In particular, hyperglycemic obese patients revealed lower spectral density in myogenic-related component than normoglycemic obese and normal weight ones. Moreover, postocclusive reactive hyperemia (PORH) was impaired in hyperglycemic obese compared to normoglycemic and normal weigh subjects. After hypocaloric diet, in hyperglycemic obese patients there was an improvement in SBF accompanied by recovery in myogenic-related oscillations and arteriolar responses during PORH. In conclusion, hyperglycemia markedly affected peripheral microvascular function; hypocaloric diet ameliorated tissue blood flow.it_IT
dc.format.extentP. 1-7it_IT
dc.language.isoenit_IT
dc.sourceUniSa. Sistema Bibliotecario di Ateneoit_IT
dc.subjectObesityit_IT
dc.subjectHyperglycemiait_IT
dc.subjectHypocaloric dietit_IT
dc.subjectMicrovascular blood flowit_IT
dc.subjectLaser oppler perfusion monitoringit_IT
dc.titleMicrovascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric dietit_IT
dc.typeArticleit_IT
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