In the last few years, computational chemistry has played an important role in disclosing novel compounds with relevant biological activity. Inflammation and cancer processes have been recently linked, and the identification ...

The aims of this work were to investigate the impact of the heat treatment on the chemical composition (holocellulose, lignin and extractives) of different wood species, to characterise and quantify wood extractives and ...

Nature is a wide source of biologically active compounds investigated with the purpose to be used as drugs due to their biological activity and also useful in pharmaceutical discovery and drug design. Nowadays, medicinal ...

Chirality plays a vital role in human daily life. After the famous but tragic case regarding the Thalidomide, Food and Drug Administration (FDA) gave a guide in relation to the submission of new drug applications... [edited ...

This PhD thesis is concerned with the design, synthesis and the characterization of new macrocyclic derivatives. Development of new macrocyclic compounds is a particularly interesting because they can involve like building ...