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Allergens in allergy diagnosis: a glimpse at emerging new concepts and methodologies
(2012)
Allergic diseases are important concern of public health. A reliable diagnosis is of utmost importance for the management of allergic patients both when immunotherapy is planned and when the treatment is essentially based ...
Environmental pollution effectson reproductive health? Clinical-epidemiological study in southern Italy
(2012)
This study aims to address the clinical, statistical and Epidemiological Relationship Between Birth Defects and Environmental Pollution, in the Campania Region and in Salerno.
Objectives: We examined four groups of subjects ...
Dopamine use in intensive care: are we ready to turn it down?
(2012)
Dopamine is still frequently used as a first line
vasopressor agent in hypotensive patients, when physicians
are afraid of noradrenaline and believe that dopamine, with
its β and α, inotrope and vasopressor effects, ...
An engineering approach to biomedical sciences: advanced testing methods and pharmacokinetic modeling
(2012)
In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical ...
1,4-Dihydropyridines: the multiple personalities of a blockbuster drug family
(2012)
More than 40 years after their introduction in therapy, 1,4-dihydropyridines (DHPs) are still amongst the most prescribed drugs in the world. Though they all share a similar mechanism of action blocking L-type voltage-gated ...
An engineering approach to biomedical sciences: advanced strategies in drug delivery systems production
(2012)
Development and optimization of novel production techniques for drug delivery systems are fundamental steps in the “from the bench to the bedside” process which is the base of translational medicine. In particular, in the ...
Sisters acts: converging signaling between CaMKII and CaMKIV, two members of the same family
(2012)
Calcium (Ca2+
) is a universal second
messenger that regulates a number of diverse cellular
processes including cell proliferation, development,
motility, secretion, learning and memory1, 2. A variety of
stimuli, ...
Pediatric health mobility: is it only an italian problem?
(2012)
Intra-regional, extra-regional and
international health mobility are important
phenomena for regional and national healthcare
planning. Pediatric data on this topic are scarce. We
therefore conducted a systematic ...