Le strutture e le attività metaboliche di tutte le cellule si basano su una vasta gamma di molecole comprendenti: amminoacidi, carboidrati, lipidi e nucleotidi, insieme alle forme polimeriche di questi composti. Ognuna di ...

Le azumammidi sono cinque ciclopeptidi di origine marina, isolate nel 2003 da Fusetani et al dalla spugna Mycale izuensis e brevettate dalla Yamanouchi Pharmaceutical. L'interesse destato da questi metaboliti secondari è ...

Macrolactones are a large and structurally diverse class of compounds. Natural products having a macrolactone structure have been isolated from many natural sources such as plants, insects, marine organism and bacteria. ...

This PhD work describes the development of different Michael and Michael type processes employing different bifunctional organocatalysts. All the processes studied involved a non-covalent activation of the substrates ...

Computational chemistry represents today a valid and fast tool for the research of new compounds with potential biological activity. The analysis of ligand-macromolecule interactions and the evaluation of possible “binding ...

Recently, Neri et al have introduced an efficient method to obtain endo-cavity complexation and through-the-annulus threading of large calixarenes exploiting the inducing effect of a weakly coordinating anion, tetrakis ...

Aim of the research project has been the synthesis of cyclopeptides and cyclopeptoids in order to investigate their structural properties and catalytic activities. In particular, studies of the arrangement and the cyclopeptoids ...

Recently, Neri et al. have introduced an efficient method to obtain endo-cavity complexation and through-the-annulus threading of large calixarenes by exploiting the inducing effect of the weakly coordinating tetrakis[3, ...

The aim of this PhD project has been to develop new synthetic strategies in enantioselective preparation of natural products. In particular my attention has been focused on preparation of some natural metabolite, containing ...

The aim of my PhD thesis was focused on the asymmetric synthesis of new heterocyclic compounds using cascade and tandem processes involving the formation of new binding Carbon-Carbon and Carbon- Heteroatom. Heterocyclic ...