Browsing Drug Discovery & Development by Subject "Cancer"
Now showing items 1-3 of 3
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Annexin A1 in pancreatic cancer progression
(Universita degli studi di Salerno, 2022-02-02)Pancreatic cancer (PC) is one of the most aggressive cancers in the world and it correlates to poor prognosis and high mortality due to late diagnosis, even if early diagnosed. Resectable PC patients have unfavorable outcome ... -
Design, synthesis and biological evaluation of small molecules able to interact with macromolecular targets involved in tumor pathology
(Universita degli studi di Salerno, 2021-05-06)Inflammation and cancer are two complex pathological processes that exploit several molecular actors. The identification of new platforms able to interfere with biological targets placed at the crossroads of these two ... -
Role of CD73 - A2A/A2B receptors axis in cancer
(Universita degli studi di Salerno, 2018-04-05)The adenosinergic pathway plays a critical role in cancer development and progression, as well as in drug resistance to chemotherapy and/or targeted-therapy. The goal of this PhD thesis was to investigate and fully ...