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Design and development of new polymeric materials with potential antimicrobial and/or antifungal activity
(Universita degli studi di Salerno, 2014-12-15)
This PhD project is focused on the development of new polymeric materials with antibacterial and antifungal activity.
The first part of the work was dedicated to the synthesis and the insertion of a modified amino acid ...
The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti-viral activity
(Universita degli studi di Salerno, 2014-05-21)
The thesis entitled “The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti-viral activity" is divided into three chapters.
The title of the thesis clearly reflects the ...
Design and synthesis of peptides that modulate apoptotic process.
(Universita degli studi di Salerno, 2014-11-17)
Oncogenic activation of tyrosine kinases is a common feature in cancer, and its regulation represents an excellent antitumoral target. Tyrosine phosphorylation is also controlled by protein-tyrosine phosphatases (PTPs). ...
In vitro and in cell functional proteomics on natural compounds
(Universita degli studi di Salerno, 2014-04-24)
Chemical proteomics has acquired a pivotal role in chemical biology because of its peculiar capability to deeply analyze the proteome from many points of view. Proteins identification, characterization and quantification ...