Cerca
Items 1-9 di 9
Synthesis, characterization and cytotoxicity studies of novel organo-metallic compounds
(Universita degli studi di Salerno, 2015-04-24)
Despite the discovery of cis-platin in the treatment of cancer there has
been a considerable exploration on the antitumoral activity of other
transition metal complexes. One of the main problems about the
application ...
Development of analytical methodology for determination of emerging contaminants in enviroment and food
(Universita degli studi di Salerno, 2015-04-24)
In recent years, fate, occurrence and potential adverse effect of emerging contaminants (ECs) in the environment have received an increased attention by scientific community. The ECs are a broad category of chemicals, ...
Design, synthesis and biological studies of novel heterocyclic compounds as anticancer drugs
(Universita degli studi di Salerno, 2015-04-24)
Heterocyles are an essencial class of molecules, assuming a role in many aspect of
our life. Indeed heterocyclic nucleus is a common feature of several biomolecule and
bioactive compounds including agrochemical products ...
Novel respirable powder formulation: design, aerosolization and permeation studies through pulmonary epithelial cell line and mucus models.
(Universita degli studi di Salerno, 2015-03-18)
Direct administration of drugs to the lungs has been used for millennia as a major treatment for a number of diseases. Origin of the inhalation therapies can be found 2000 B.C in India, where people were used to smoke ...
Analysis and evaluation of potential nutracentical milk and dairy products derived from the Centrale del latte di Salerno
(Universita degli studi di Salerno, 2015-03-16)
The main objective of my PhD has been focused to the analysis and characterization of milk and dairy products derived from “Centrale del Latte di Salerno” in order to assess their potential use as dietary supplements and ...
Design and structural optimization of new molecules as potential antiinflammatory and/or anticancer agents.
(Universita degli studi di Salerno, 2015-03-10)
L’infiammazione ed il cancro sono due complessi meccanismi patologici in cui risultano coinvolti una serie di differenti mediatori molecolari. La profonda connessione tra cancro ed infiammazione è ben nota e la modulazione ...
Characterization and biological properties of Citrus industrial derivatives and waste products for the formulation of nutraceuticals
(Universita degli studi di Salerno, 2015-03-16)
Polyphenols are natural chemical compounds, common in higher plants as and particularly known and appreciated for their health properties. We focused attention on Citrus bergamia, Citrus sinensis, Mela annurca and Vitis ...
NMR study of protein-ligand interaction
(Universita degli studi di Salerno, 2015-03-11)
My PhD project was focused on the study of protein-ligands interactions using different NMR techniques. NMR has a long history in drug discovery and hit-to-lead optimization. Compared to many other biophysical techniques, ...
Design, synthesis and biological evaluation of new small molecules with anti-inflammatory activity
(Universita degli studi di Salerno, 2015-03-18)
Per lipossigenasi (nota più comunemente con l'abbreviazione di LOX o LO) si intende una famiglia eterogenea di enzimi in grado di perossidare i lipidi e di causare l'ossigenazione di acidi grassi polinsaturi trasformandoli, ...