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Study of bio-molecar interaction: a) Mapping of the interaction between STAT1 and flavonoids; b) Role of PDIA6-BiP complex in the regulation of the unfolded protein response
(Universita degli studi di Salerno, 2012-03-21)
Mapping of the interaction between STAT1 and flavonoids
Abstract
An experimental approach is described, in the first part of this Ph.D. work, for determining protein-small molecule non-covalent ligand binding sites and ...
Integrated metabolomics approaches for berry fruit used in nutraceutical formulations
(Universita degli studi di Salerno, 2016-04-13)
The species under investigation during these three years of PhD course were: Fragaria ananassa, Fragaria vesca, Morus alba, Morus nigra and Myrtus communis. All these species are characterized by the production of small ...
Techniques of proteomic analysis as tools for studies in biomedical field
(Universita degli studi di Salerno, 2017-03-24)
It is known that prenatal exposure to pollutants and particularly heavy metals can have long term damaging consequences on infants, due to their accumulation in-body. Since the 1990s, ten million tonnes of waste have been ...
Exploring the chemical diversity in marine organisms: new molecules for pharmaceutical applications
(Universita degli studi di Salerno, 2012-02-23)
It is increasingly recognized that the oceans preserve a huge number of natural products and novel chemical entities, with biological activities that may be useful in the quest for finding drugs with greater efficacy and ...