http://elea.unisa.it/xmlui/handle/10556/2093 2026-04-20T13:49:27Z 2026-04-20T13:49:27Z Solazzo, Antonio D'Auria, Valeria Moccia, Livio Vatrella, Alessandro Bocchino, Marialuisa Rea, Gaetano http://elea.unisa.it/xmlui/handle/10556/3865 2025-04-30T14:30:10Z 2016-01-01T00:00:00Z

Title: Posterior mediastinal extramedullary hematopoiesis secondary to hypoxia Authors: Solazzo, Antonio; D'Auria, Valeria; Moccia, Livio; Vatrella, Alessandro; Bocchino, Marialuisa; Rea, Gaetano Abstract: Two mediastinal masses were incidentally detected at high resolution computed tomography (HRCT) of a 72 year-old male patient, former smoker, affected by chronic obstructive pulmonary disease with worsening dyspnea and 2-year medical history of polycythemia secondary to hypoxia. Integration with a multidetector computed tomography (MDCT) scan after administration of intravenous injection contrast medium showed slightly inhomogeneous increase of enhancement of masses, suggesting in the first case potential malignancy. Diagnosis of extramedullary hematopoiesis was achieved by fine needle aspiration citology (FNAC). Extramedullary hematopoiesis must be considered in differential diagnosis in patients with medical history of polycythemia and severe hypoxia.

2016-01-01T00:00:00Z Merolla, Giovanni Tartarone, Antonio Porcellini, Giuseppe http://elea.unisa.it/xmlui/handle/10556/3864 2025-04-30T14:33:24Z 2016-01-01T00:00:00Z

Title: Clinical and radiographic mid-term outcomes after total shoulder replacement: a retrospective study protocol including 400 anatomical and reverse prosthetic implants Authors: Merolla, Giovanni; Tartarone, Antonio; Porcellini, Giuseppe Abstract: Objectives: To obtain outcomes data on anatomical and reverse total shoulder arthroplasty by analysis of clinical scores and standard radiographs. Subject selection and enrollment: 400 consecutive series of patients replaced with anatomical and reverse total shoulder arthroplasty (minimum 3 years follow-up). Study Design: retrospective monocenter. Preoperative assessment: Demographics, clinical scores (Constant-Murley) as available, shoulder X-ray (AP, outlet and axillary views) . Last follow-up: Postoperative radiographhs and clinical scores. Adverse events and complications to be reported as occurred since implantation. Statistical analysis: Data collected will be summarized and analyzed for statistical significance.

2016-01-01T00:00:00Z Liccardi, Gennaro Triggiani, Massimo Piccolo, Amedeo Salzillo, Antonello Parente, Roberta Manzi, Flavio Ricardo Vatrella, Antonio http://elea.unisa.it/xmlui/handle/10556/3863 2025-04-30T14:30:10Z 2016-01-01T00:00:00Z

Title: Sensitizazion to common and uncommon pets or other furry animals: which may be common mechanisms? Authors: Liccardi, Gennaro; Triggiani, Massimo; Piccolo, Amedeo; Salzillo, Antonello; Parente, Roberta; Manzi, Flavio Ricardo; Vatrella, Antonio Abstract: Exposure to animal allergens constitutes a relevant risk factor for the development of allergic sensitization. Moreover, an increasing number of people become owners of less common animals. In this article we summarize aspects related to sensitization to cat/dog which may be applied also to uncommon pets or other furry animals. The data discussed here suggest that several different factors may induce allergic sensitization to furry animals with or without previous contact. Allergic sensitization without animal exposure is a relevant risk for patients because they are not aware about the possibility that even severe respiratory symptoms may develop after an occasional animal contact. This aspect should be taken into account by susceptible individuals before acquiring pets or beginning a contact for working/leisure activity with a common as well as uncommon animal. As a consequence, skin prick test and/or evaluation of specific IgE antibodies (by classic ImmunoCAP or micro-array technique ImmunoCAP ISAC) also to less common ("new") mammalian allergens could be recommended in individuals already sensitized to common pets to identify the occurrence of allergic sensitization and consequently to avoid future exposures to uncommon animal allergens.

2016-01-01T00:00:00Z Nicolin, Vanessa Baldini, Giovanna De Iaco, Doriano Bortul, Roberta Turco, G. Nori, Stefania Lucia http://elea.unisa.it/xmlui/handle/10556/3862 2025-04-30T14:33:25Z 2016-01-01T00:00:00Z

Title: Looking for calcium phosphate composite suitable to study osteoclast endocytosis: preliminary observations Authors: Nicolin, Vanessa; Baldini, Giovanna; De Iaco, Doriano; Bortul, Roberta; Turco, G.; Nori, Stefania Lucia Abstract: One of the issues regarding in vitro study of bone resorption is the synthesis of a bonelike biomaterial forming a thin layer onto either glass or plastic. The synthesis of a bone-like material suitable for in vitro studies can be valuable both to investigate osteoclast differentiation, that in vivo proceeds within the local microenvironment of bone and to understand how its presence triggers activation of macrophages present in situ when bone is damaged (a scenario that can occur for example in case of bone fracture). Despite the intensive studies committed to recreate synthetic bone analogues, the most used substrates for in vitro studies on bone resorption are slices of bone or dentine. Therefore morphological investigations (i.e. fluorescence analysis and phase contrast) are strongly compromised due to the thickness of the bone analogue. In the present study, with the aim to guarantee a versatile (and easy to be made) substrate, that could be suitable to study cell adhesion and morphology by epifluorescence, phase contrast and TEM, we developed a biomaterial containing a calcium phosphate salt and type I collagen. This material (made specifically for in vitro studies) forms a very thin layer that allowed to merge the morphological information derived from phase-contrast and epifluorescence observation, making possible the observation of the interface between cell and matrix. Moreover the electron microscopy evaluation of the endocytosis performed on cell differentiated could be more suitable because sample does not need the process of demineralization.

2016-01-01T00:00:00Z