DSpace Collezione:
http://elea.unisa.it/xmlui/handle/10556/4466
2024-03-28T18:13:20ZLeg fracture associated with synostosis of interosseous membrane during running in a soccer player
http://elea.unisa.it/xmlui/handle/10556/4498
Titolo: Leg fracture associated with synostosis of interosseous membrane during running in a soccer player
Autori: Oliva, Francesco; Buharaja, Rodrigo; Iundusi, Riccardo; Tarantino, Umberto
Abstract: ntroduction - Leg fractures may occur frequently in
sport injuries but it is very rare to find this kind of
injury associated with interosseous membrane
synostosis. This case report describes a unique case
of 42 B1.2 fracture of the leg associated with an
interosseous membrane synostosis and literature
review on Pubmed, Google scholar and Medscape.
Case Presentation - A 26 year old male amateur
soccer player came to our attention at the emergency
room after a fall while he was running without any
direct trauma following a referred ankle sprain. X-ray
and CT scan of the left leg showed a comminuted
displaced fracture of the lower middle third of tibial
and peroneus diaphysis, and moreover, a fracture of
peroneal malleolus associated with a bone bridge
between the tibia and fibula. The patient was treated
with a surgical osteosynthesis the day after trauma.
Conclusion - We think that the interosseous
membrane plays an important role in biomechanics of
the leg even during running. To our knowledge, this
is the first case reported which show the fractures of
the tibia and fibula associated with an ipsilateral
synostosis of the interosseous membrane.
Class of evidence: Level V.2017-01-01T00:00:00ZElective orthopaedic and trauma patients in southern italy are vitamin d deficient. A pilot study.
http://elea.unisa.it/xmlui/handle/10556/4497
Titolo: Elective orthopaedic and trauma patients in southern italy are vitamin d deficient. A pilot study.
Autori: Foccillo, Antonio; Aicale, Rocco; Maffulli, Nicola
Abstract: Many patients present with Vitamin D (Vit d; 25 (OH) D)
deficiency on admission to hospital. The present study
evaluated the levels of serum concentration of 25 (OH) D
in patients undergoing elective arthroplasty of the hip and
knee and in patients with proximal femur fracture. A total
of 90 patients of both sex were recruited, 20 with
osteoarthritis of the knee, 29 with osteoarthritis of the hip,
and 41 with a hip fracture. The levels of Vit D were
measured twice: on admission and on the fourth day after
surgery. In patients undergoing knee arthroplasty, the
levels of Vit D were 16.85 ng/ml in the preoperative and
18.235 ng/ml in the postoperative period. In patients
undergoing hip arthroplasty, we found levels <4.20 ng/ml
for men, while in women 25.20 ng/ml pre-operatively and
22.8 ng/ml post-operatively. In patients with a hip
fracture, men progressed from very low levels
preoperatively (6.38 ng/ml) with post-operative levels of
18.44 ng /ml. Women exhibited a slight improvement from
12.24 ng/ml pre-operatively to 17.9 ng/ml postoperatively. Patients who are candidates for hip and knee
arthroplasty and in hip fracture patients exhibit low Vit D
levels. The activation of the inflammatory cascade may
induce reduction of Vit D levels, and this fall is associated
with impaired bone health.2017-01-01T00:00:00ZMicroRNs and cardiovascular diseas es: from bench to beside
http://elea.unisa.it/xmlui/handle/10556/4496
Titolo: MicroRNs and cardiovascular diseas es: from bench to beside
Autori: De Rosa, Roberta; Polito, Maria Vincenza; Benvenga, Rossella Maria; De Angelis, Elena; Piscione, Federico; Galasso, Gennaro
Abstract: MicroRNAs (microRNAs or miRs) are small, noncoding RNAs that control gene expression by binding to
and repressing specific mRNA target and have emered
as powerful regulators of many biological processes.
Understanding miRNAs-biology and functions may be
pivotal to get a better insight into pathophysiological
mechanisms responsible for a large number of morbid
conditions and may lay the foundations for the
development of novel therapeutic interventions.
Moreover, besides their intracellular functions, miRs are
present in the human circulation in a remarkably stable
cell-free form, and their plasmatic levels have been
proposed as biomarkers for several pathological
conditions. The present review aims to summarize the
current evidences with regard to biological role of
miRNAs in cardiovascular system and their
involvement in the pathogenesis of cardiovascular
diseases including atherosclerosis, heart failure and
pathological heart and vascular remodelling and to
highlight their potential use as novel biomarkers and as
therapeutic targets in cardiac and vascular diseases.2017-01-01T00:00:00ZTranscatheter implantable devices to monitoring of elevated left atrial pressures in patients with chronic heart failure
http://elea.unisa.it/xmlui/handle/10556/4495
Titolo: Transcatheter implantable devices to monitoring of elevated left atrial pressures in patients with chronic heart failure
Autori: De Rosa, Roberta; Piscione, Federico; Schranz, Dietmar; Citro, Roberta; Iesu, Severino; Galasso, Gennaro
Abstract: Elevated left atrial (LA) pressures are associated
with poor prognosis in heart failure (HF). Invasive
monitoring of LA-pressures and direct mechanical LAdecompression are associated with functional
improvement in patients suffering from HF both with
reduced and preserved ejection fraction. We aim to
review the current available percutaneously implantable
sensors for haemodynamic telemonitoring of LApressures (direct LAP sensor device- HeartPOD; right
ventricular device- Chronicle; pulmonary artery deviceCardioMEMs).2017-01-01T00:00:00Z