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Chemical proteomics on ligand protein
(2011-03-18)
The emerging field of mass spectrometry-based chemical proteomics provides a powerful instrument in the target discovery of bioactive small-molecules, such as drugs or natural products[1]. The identification of their ...
A multi-disciplinary approach based on mass spectrometry to disclose the potential of phytoextracts as natural cosmetics
(2023-04-09)
Plant cells represent a valid source of cosmetic ingredients since their extracts can be considered bio-sustainable, contaminant-free and standardized secondary metabolites mixtures (Barbulova et al., 2014). This PhD project ...
Targeted and untargeted proteomic approaches to disclose small molecules interactome
(2023-04-24)
The identification of natural products and synthetic compounds target proteins is pivotal to
understand their mechanism of action for the development of molecular probes and/or potential drugs.
Functional proteomics is a ...
In vitro and in cell functional proteomics on natural compounds
(2014-04-24)
Chemical proteomics has acquired a pivotal role in chemical biology because of its peculiar capability to deeply analyze the proteome from many points of view. Proteins identification, characterization and quantification ...