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Stereoselectivity in asymmetric processes and molecular assemblies
(2020-02-19)
The aim of this thesis was to explore different areas of organic chemistry in which the
stereocontrol in the design of chemical processes and/or molecular assemblies is necessary.
Therefore, the stereoselectivity in ...
Interactome analysis of bioactive molecules: optimization of a functional proteomics platform
(2020-10-24)
The identification of natural products (NPs) target proteins is pivotal to understand their
mechanism of action, in order to develop molecular probes and/or potential drugs. In the last 15 years,
affinity chromatography-coupled ...
Study on calixarene threading: towards molecular machines
(2021-05-11)
Negli ultimi tre decenni, l'uso dei calixareni come host macrociclici nella chimica
supramolecolare ha acquisito una rilevanza crescente, soprattutto per la costruzione di
macchine molecolari. Pertanto, è importante capire ...
New insights into peptoids' chemistry: synthesis, characterization and properties
(2016-05-11)
My PhD research activity aimed to enrich the realm of peptoids1 with novel compounds and new insights into their behavior and properties, investigating their potential applications.
A new class of cyclic “arylopeptoids” ...
Chiral organocatalysts mediated asymmetric oxyfunctionalization and tandem reaction
(2015-03-13)
Asymmetric organocatalysis is a new rapidly growing field whose huge potential is becoming more and more evident.This PhD project has been conceived and developed in the context of non-covalent organocatalysis.
The aim of ...
Development of new in vitro models based on the use of electrospun scaffolds and their imaging by multiphoton microscopy coupled with fluorescence lifetime imaging microscopy
(2018-02-22)
In this thesis, new possible applications of electrospun scaffolds are presented. Besides, the interaction of human dermal fibroblasts (HDFs) with the materials has been investigated using multiphoton microscopy (MPM) ...
Innovative applications of stable carbon isotope ratio in environmental and food chemistry
(2018-03-08)
In the last year, the stable isotope ratio analysis has become a useful tool with many applications in different scientific area. In particular the characteristic isotope signature of materials has permitted to identify ...
Supramolecular Scaffolds for Biomimetic Catalysis
(2018-03-02)
This PhD thesis is concerned with the design, synthesis and the characterization of supramolecular scaffolds for biomimetic catalysis. Development of new organocatalytic systems based upon well-designed calix[4]arene ...
Structural studies, design, identification and biological evaluation of bioactive compounds settore
(2016-04-04)
Computational methodologies in combination with experimental biological assay represent fundamental key tools in the drug discovery process. The study of ligand-macromolecule interactions has a crucial role for the design, ...
Cavity Filling and Chirality Effects in Calixarene Threading
(2016-03-16)
In 2010, the Prof. Neri’s group showed that the calix[6]arene hosts were able to recognize dialkylammonium axles when they were coupled with the weakly coordinating Tetrakis[3,5 bis(triFluoromethyl)Phenyl]Borate (TFPB−) ...