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dc.contributor.advisorCapasso, Letizia
dc.contributor.advisorBorrelli, Angela Carla
dc.contributor.advisorCerullo, Julia
dc.contributor.advisorPisanti, R.
dc.contributor.advisorFigliuolo, C.
dc.contributor.advisorIzzo, Federica
dc.contributor.advisorPaccone, M.
dc.contributor.advisorFerrara, Teresa
dc.contributor.advisorLama, Silvia
dc.contributor.advisorRaimondi, Francesco
dc.date.accessioned2015-01-29T13:14:32Z
dc.date.available2015-01-29T13:14:32Z
dc.date.issued2015
dc.identifier.citationCapasso L, Borrelli AC, Cerullo J, Pisanti R, Figliuolo C, Izzo F, Paccone M, Ferrara T, Lama S, Raimondi F. Role of Immunoglobulins in Neonatal Sepsis. Translational Medicine @ UniSa 2015, 11(5):28-33en_US
dc.identifier.issn2239-9747en_US
dc.identifier.urihttp://hdl.handle.net/10556/1647
dc.identifier.urihttp://dx.doi.org/10.14273/unisa-451
dc.description.abstractNeonates, especially VLBW, are at high risk for sepsis related morbidity and mortality for immaturity of their immune system and invasive NICU practices. The paucity of immunoglobulins in preterm neonates consequently to the immaturity of immune system contributes to their high risk for systemic infection. The use of intravenous IgM enriched immunoglobulins, with higher antimicrobial activity than standard IgG, has been demonstrated in a retrospective study to reduce short term mortality in VLBW infant with proven sepsis. Larger, randomized prospective trials given the enormous burden of morbidity and mortality imposed by neonatal sepsis should urgently be addressed not only to validate this results but also to tailor the optimal scheme of treatment.en_US
dc.format.extentP. 28-33en_US
dc.language.isoenen_US
dc.sourceUniSa. Sistema Bibliotecario di Ateneoen_US
dc.subjectNeonateen_US
dc.subjectImmunoglobulinsen_US
dc.subjectSepsisen_US
dc.titleRole of Immunoglobulins in Neonatal Sepsisen_US
dc.typeArticleen_US
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