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Design, synthesis and biological evaluation of new small molecule modulators of Arginine methyltransferases
(2011-02-21)
The methylation of arginine residues is a prevalent post-translational modification, found on both nuclear and cytoplasmic proteins, catalyzed by the protein arginine N-methyltransferase (PRMT) family of enzymes. To date ...
Design, synthesis and pharmacological evaluation of new enzyme inhibitors
(2023-04-13)
My PhD research plan relates to the exploration of the structural requirements for the modulation
of enzymes involved in the pathogenesis of viral infections and inflammatory disorders. The first part
of my doctoral project ...