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dc.contributor.authorCavaliere, Matteo
dc.contributor.authorDe Luca, Pietro
dc.contributor.authorDe Santis, Carla
dc.contributor.authorScarpa, Alfonso
dc.contributor.authorRalli, Massimo
dc.contributor.authorDi Stadio, Arianna
dc.contributor.authorViola, Pasquale
dc.contributor.authorChiarella, Giuseppe
dc.contributor.authorCassandro, Claudia
dc.contributor.authorCassandro, Francesco Maria
dc.date.accessioned2021-08-02T08:23:04Z
dc.date.available2021-08-02T08:23:04Z
dc.date.issued2020
dc.identifier.citationCavaliere, M, De Luca, P, De Santis, C, Scarpa, A, Ralli, M, Di Stadio, A, Viola, P, Chiarella, G, Cassandro, C, Cassandro, F. (2020). Drug-Induced Sleep Endoscopy (DISE) with Simulation Bite to Predict the Success of Oral Appliance Therapy in Treating Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS). Translational medicine @ UniSa 2020, 23: 58–62it_IT
dc.identifier.issn2239-9747it_IT
dc.identifier.urihttp://www.translationalmedicine.unisa.it/indexit_IT
dc.identifier.urihttp://elea.unisa.it:8080/xmlui/handle/10556/5696
dc.identifier.urihttp://dx.doi.org/10.14273/unisa-3800
dc.description.abstractStudy objectives: Oral appliances have gained their place in the treatment of obstructive sleep apnea (OSA) where custom-made titratable mandibular advancement devices (MAD) have become the oral appliance of choice. This study aimed to asses the value of the drug-induced sleep endoscopy (DISE) using a MAD in the prediction of treatment outcome for OSAHS Methods: This is a prospective, single-center cohort study that enrolled sixty-six consecutive patients with diagnosed OSA (5 events/h < apneahypopnea index (AHI) < 50 events/h) to be treated with a custom-made titratable MAD. The patients were evaluated polysomnographically with the MAD in situ after the adaptation and titration period of 3 months. The associations between findings during DISE and treatment outcome were assessed Results: The subjects showed a wide range of severity of OSAHS pre-treatment: median AHI was 43.10 with a range from 20.13 to 66.07. The simulation bite was associated with a significant increase in cross-sectional area at level of the velopharynx, tongue base and epiglottis. MAD treatment response in the studied population was 91%, with a mean AHI improving from 43.10 to 12.93. Conclusions: Drug-induced sleep endoscopy with simulation bite is an acceptably reproducible technique for determining the sites of obstruction in OSAHS subjects; it thus offers possibilities as a prognostic indicator for treatment with MADit_IT
dc.format.extentP. 58-62it_IT
dc.language.isoenit_IT
dc.sourceUniSa. Sistema Bibliotecario di Ateneoit_IT
dc.subjectOral applianceit_IT
dc.subjectDrug-induced sleep endoscopyit_IT
dc.subjectNasendoscopyit_IT
dc.subjectSimulation biteit_IT
dc.subjectObstructive sleep apneait_IT
dc.titleDrug-induced Sleep Endoscopy (DISE) with Simulation Bite to Predict the Success of Oral Appliance Therapy in Treating Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)it_IT
dc.typeJournal Articleit_IT
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