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dc.contributor.authorCavallo, Luigi M.
dc.contributor.authorSolari, Domenico
dc.contributor.authorSomma, Teresa
dc.contributor.authorDi Somma, Alberto
dc.contributor.authorChiaramonte, Carmela
dc.contributor.authorCappabianca, Paolo
dc.date.accessioned2013-11-21T13:02:17Z
dc.date.available2013-11-21T13:02:17Z
dc.date.issued2013
dc.identifier.citationCavallo L M, Solari D, Somma T, Di Somma A, Chiaramonte C, Cappabianca P. Use of equine pericardium sheet (lyomesh®) as dura mater substitute in endoscopic endonasal transsphenoidal surgery. Translational Medicine @ UniSa 2013;7(5):23-28en_US
dc.identifier.issn2239-9747en_US
dc.identifier.urihttp://hdl.handle.net/10556/866
dc.description.abstractObjective: The aim of this study was to describe the use of equine pericardium sheet (Lyomesh®) as dural substitute for sellar reconstruction after endoscopic endonasal transsphenoidal surgery for the removal of pituitary adenomas. Methods: We reviewed data of patients that underwent surgery by means of an endoscopic endonasal transsphenoidal approach for the removal of pituitary adenomas over a 12-months period, starting in May 2012, i.e. when we adopted Lyomesh® (Audio Technologies, Piacenza, Italy) an equine pericardium sheet, as dura mater substitute. Results: During the 12-months period evaluated, we performed an endoscopic endonasal transsphenoidal operation for a variety of pituitary lesions on 102 consecutive patients. Among these, in 12 patients (9.4%) harboring a pituitary adenoma, the implant of the pericardium sheet was used. Four patients (33.3%) presented a small intraoperative cerebrospinal fluid (CSF) leak; in these cases the Lyomesh® was placed intradurally with fibrin glue and, thereafter, several layers were positioned in extradural space. In 8 other subjects without any evidence of CSF leak, the dural substitute was placed intradurally and fibrin glue was injected intradurally to hold the material in place. Conclusions: Even if based on a relatively small patient series, our experience demonstrated that the use of equine pericardium sheet (Lyomesh®) as dura mater substitute in transsphenoidal surgery is safe and biocompatible, as compared with other dural substitutes.en_US
dc.format.extentP. 23-28en_US
dc.language.isoenen_US
dc.sourceUniSa. Sistema Bibliotecario di Ateneoen_US
dc.subjectEndoscopic endonasal surgeryen_US
dc.subjectSkull base reconstructionen_US
dc.subjectCSF leaken_US
dc.subjectDural substitutesen_US
dc.titleUse of equine pericardium sheet (lyomesh®) as dura mater substitute in endoscopic endonasal transsphenoidal surgeryen_US
dc.typeArticleen_US
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