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Functional and metabolic brain correlates in hearing loss and rehabilitation
(2021-04-19)
The human auditory system serves the role of extracting information from objects in the environment engaging in analyses of the auditory world so that the listener can accomplish the goal of learning and communication. ...
Untargeted metabolomics as a diagnostic tool in NAFLD: discrimination of steatosis, steatohepatitis and cirrhosis
(2021-05-07)
Introduction: Non-Alcoholic Fatty Liver Disease encompasses a spectrum of diseases ranging from simple steatosis to steatohepatitis (or NASH), up to cirrhosis and hepatocellular carcinoma(HCC). The challenge is to recognize ...
Post-transcriptional gene regulatory networks in chronic airway inflammation: role of RNA-binding proteins
(2020-05-06)
Background. RNA-binding proteins (RBPs) play a key role in post-transcriptional gene regulation (PTGR) of genes involved in numerous biological processes. These proteins act through the binding to specific cis-elements ...
Development of a bioengineered three-dimensional scaffold able to commit stem cells toward tenogenic phenotype
(2021-06-23)
The term tendinopathy is a generic descriptor of tendon disorders. Spontaneous adult
tendon healing results in scar tissue formation and fibrosis, with impaired biological
and mechanical properties. Adult tendons have a ...
Cognitive and behavioral features in atypical parkinsonian syndromes
(2020-08-14)
Introduction Progressive supranuclear palsy (PSP), Multiple system atrophy (MSA), corticobasal degeneration (CBD) and dementia with Lewy Bodies (DLB) are included in atypical parkinsonisms (AP) and they typically involve ...
Espressione genica indotta dall'ormone somatotropo nei monociti di bambini sani e con deficit di GH
(2020-07-13)
Somatotropic hormone (GH) has transcriptional effects on the cells of many organs, directly by activating its receptor (GHR) or indirectly through induction of IGF-1 or other mediators. The presence of GHR in almost all ...
Role of vitamin D in the modulation of chronic bowel inflammation and in the genesis of bone mass loss in patients with inflammatory bowel diseases
(2020-07-09)
Background: Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of the gastrointestinal tract consisting two principal categories, ulcerative colitis (UC) and Crohn’s disease (CD). Bone ...
Clinical characterization, genetic screening and genotype-phenotype associations in cerebellar and brainstem congenital defects
(2020-10-01)
Cerebellar and brainstem congenital defects (CBCDs) represent a wide spectrum of malformative
disorders resulting from abnormal development of midbrain-hindbrain and characterised by high
clinical and genetic heterogeneity. ...
Circulating sortilin level as a potential biomarker for endothelial dysfunction and hypertension
(2022-03-16)
Sortilin has been positively correlated with vascular disorders in humans. Previous studies
showed that sortilin promotes activation of acid sphingomyelinase (ASMase) and
subsequently induces an increase of nicotinamide ...
Studying the "neural behavior": a perspective on bridging the gap between behaviorism and neuroscience and its applications to language teaching strategies
(2021-07-09)
The purpose of my thesis is to point out the development of a particular line of research aimed at
bridging the gap between the Neurosciences and Behavior Analysis, the science of behavior and
learning, by studying verbal ...