Fisiopatologia, diagnostica e terapia molecolare delle malattie metaboliche

Novel Insights into the Biological Effects of the Isoprenoid Derivative N6-Isopentenyladenosine: Involvement of the Metabolic Sensor Ampk in Angiogenesis Inhibition

Picardi, Paola (Universita degli studi di Salerno, 2014-03-19)

N6-isopentenyladenosine (iPA) is a modified adenosine characterized by an isopentenyl chain derived by dimethylallyl pyrophosphate (DMAPP), an intermediate of the metabolic pathway of mevalonate, that is known to be ...
p53 regulates Mevalonate Metabolic pathway

D'Alessandro, Alba (Universita degli studi di Salerno, 2014-03-14)

The mevalonate pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, I provided evidences about genetic and pharmacologic perturbation of p53, which directly influenced ...
The transcription factor Prep1 regulates adipose tissue functions

Liotti, Antonietta (Universita degli studi di Salerno, 2014-03-21)

Adipose tissue is crucial for maintaining energy and metabolic homeostasis and its functionality is closely related to the adipocytes differentiation state. Adipogenesis is regulated by several transcription factors. Prep1 ...