Area Scienze chimiche, fisiche, matematiche: Recent submissions
Now showing items 1-20 of 293
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Exploring batch and flow catalytic reactions as valuable tools for safer and greener synthesis of APIs and their fluorine intermediates
(Universita degli studi di Salerno, 2022-06-06)Il gruppo trifluorometiltio (SCF3) assume un ruolo chiave nel campo della scoperta di farmaci grazie alle sue proprietà uniche. Il forte carattere elettron-attratore e lipofilo rende vantaggiosa la sua incorporazione ... -
Artificial Intelligence methods for supporting biomedical data analysis
(Universita degli studi di Salerno, 2022-05-06)Artificial intelligence (AI) is a fundamental technology useful in many fields, ranging from finance, weather forecast, to medicine. Positive results are reached especially in the diagnostic field, where AI provides a ... -
New metal catalysts for Ring-Opening Polymerization of cyclic esters
(Universita degli studi di Salerno, 2022-05-28)I problemi ambientali ed economici legati ai polimeri derivanti da fonti petrolchimiche hanno spinto la ricerca accademica verso lo sviluppo di alternative green e degradabili rispetto alle plastiche convenzionali. I ... -
Idenffication of potyphenols in grape pomuce and newsynthetíc approaches to 2'3' diaryl-2,3- dihydribioro?uronr, uríIuí oitíve ingredients agaínst degenerutíve diseuses
(Universita degli studi di Salerno, 2022-02-10)The PhD project is divided in two main studies, the first concerning in the identification of polyphenols in Grape Pomace and the second in developing new synthetic approaches to 2,3-disubstituted-2,3- dihydlobenzofurans. The ... -
Synthesis and cascade reactions of new heterocyclic compounds
(Universita degli studi di Salerno, 2022-02-28)More than 70% of modern organic chemistry is focused on the synthesis and application of new heterocyclic compounds in many different areas, from pharmaceuticals to agrochemicals, antioxidants or dyes. Heterocyclic ... -
Technical Debt in Software Development: A Multi-Perspective Investigation
(Universita degli studi di Salerno, 2022-03-25)I prodotti software devono essere costantemente manutenuti e aggiornati per sopravvivere e continuare a soddisfare le esigenze di aziende e utenti. Agli sviluppatori viene spesso richiesto di eseguire attività di ... -
Quality and Privacy-aware (Linked) Open Data Exploitation
(Universita degli studi di Salerno, 2022-04-26)Data are the new oil and it is widely recognised the role of publishing them as Open Data to let data consumers freely access and exploit them. Data providers are not only encouraged to publish data but to ensure that ... -
Tailoring the structural and surface properties of TiO2 thin films and TiO2-based nanolayers, with heat treatments, layer thickness, and oxide mixtures
(Universita degli studi di Salerno, 2021-12-15)Titanium dioxide (TiO2), also known as titanium (IV) oxide or titania, is naturally available on the Earth as a bright, fine, and white pigment. Thanks to its unique properties, such as high refractive index, chemical ... -
Copolymerization of olefins with polar monomers by transition metal catalysts
(Universita degli studi di Salerno, 2022-06-13)The investigation into copolymerizing olefins by Ni(Il) complexes bearing pyridylimine ligands was achieved in this study. The complexes, in the presence of a proper activating agent, were found to generate active catalysts ... -
A computational approach to investigate the interactions between potential pharmacological chaperones and GALT enzyme
(Universita degli studi di Salerno, 2023-03-13)Classic galactosemia is an inborn error of metabolism associated with mutations that impair the activity and the stability of the dimeric enzyme galactose-1-phosphate uridylyltransferase (GALT), which catalyzes the ... -
Macrocycles: new properties and applications
(Universita degli studi di Salerno, 2023-06-02)Peptoids (polymers of N-substituted glycines) constitute a fascinating class of biomimetic oligoamides as peptides but exhibiting distinct structural and biological features. Cyclic peptoids, macrocycles derived from the ... -
Security and Privacy Concerns within Smart Environments: User-Centered Approaches for Defining Secure Trigger-Action Programs
(Universita degli studi di Salerno, 2023-06-13)The advent of the Internet of Things (IoT) paradigm has launched a new world of opportunities, bringing with it a new understand ing of objects and technology that, today, is all around us. In fact, especially in domestic ... -
Properties and Applications of Nanoporous-Crystalline Polymers
(Universita degli studi di Salerno, 2023-02-28)Nanoporous-crystalline (NC) forms, i.e. crystalline structure presenting nanocavities or nanochannels inside the crystalline lattice, are possible only for two polymers, both commercially available: syndiotactic polystyrene ... -
Molecular Properties Via Induced Current Densities
(Universita degli studi di Salerno, 2024-02-22)The PhD thesis written by Francesco F. Summa on Molecular Properties via Induced Current Densities is a careful report of a highly qualified and innovative research. Sixteen peer-reviewed publications on renowned journals ... -
Hidden Structures and Conflicting Items in Combinatorial Optimization Problems
(Universita degli studi di Salerno, 2023-02-14)Combinatorial optimization-based methods are widely used to solve complex real life problems. In this thesis, we use some of these methods for addressing several emerging combinatorial opti- mization problems on graphs ... -
Sustainable approaches for the synthesis and the chemical degradation of polyesters
(Universita degli studi di Salerno, 2023-03-03)Petrochemical-based plastics have a significant impact on modern society, as underlined by their high production and countless applications. Indeed, the production of plastics has increased over the past 50 years, reaching ... -
Advanced Modeling of Microlensing Events
(Universita degli studi di Salerno, 2023-04-17)The search for exoplanets is one of the most exciting challenges. From the first exoplanets discovered around the pulsar PSR B1 257+12 back in 1992 until today there are over 5200 exoplanets discovered. And the number ... -
Intelligent technologies for threat detection in networks security scenarios
(Universita degli studi di Salerno, 2023-06-08)The advent of the Internet of Things (IoT), with the consequent changes in network architectures and communication dynamics, has strongly conditioned the security market by radically shifting traditional per- ceptions ... -
Biological effects of synthetic compounds and bioactive molecules in human cell models
(Universita degli studi di Salerno, 2023-06-06)During the course of my Ph.D., I focused my studies on two main topics: the cytotoxic effects induced by 4-nonylphenol (4-NP) and 4-octylphenol (4-OP) and the anti-cancer properties of natural cardenolides extracted from ... -
Metodi matematici e tecnologie per la trasformazione digitale e le tokenizzazioni
(Universita degli studi di Salerno, 2023-03-08)This work has a two-fold objective, achieved through two lines of research. The first, purely industrial, focuses on the technical-scientific difficulties related to collecting, tokenizing, and producing value from ...