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Items 11-20 di 24
Regolazione epigenetica dell’espressione del fattore peptidico gastrointestinale TFF1
(Universita degli studi di Salerno, 2016-04-19)
TFF1 is a protein expressed in the gastrointestinal tract, belonging to the trefoil folding factor family, characterized by a conserved “trefoil domain” containing six cysteine residues that form a cloverleaf disulfide ...
New Encapsulation Technologies for The Development of in Situ Gelling Micro- Nano Particulate Systems for The Wound Healing
(Universita degli studi di Salerno, 2016-03-16)
The Ph.D project titled “New Encapsulation technologies for the development of in situ gelling micro-nano particulate systems for the wound healing” aimed to develop novel topical formulations by innovative technologies, ...
Trattamento delle fratture blow-out dell’orbita: endoscopia versus chirurgia tradizionale
(Universita degli studi di Salerno, 2016-05-04)
In the last decades, diagnostical imaging, surgical techniques, alloplastic materials,
and surgical instruments development, allowed a great progress in management of
orbital fractures. The aim of the present study was ...
Role of Annexin A1 in tumor progression
(Universita degli studi di Salerno, 2016-10-06)
Annexin 1 (ANXA1) is a multifunctional protein of 37 kDa, and represents the first characterized member of the annexin superfamily, so called since their main property is to bind (i.e. to annex) cell membranes in Ca2+-dependent ...
Progettazione di un biosensore ottico per la determinazione atmosferica del benzene
(Universita degli studi di Salerno, 2016-04-15)
In recent years, environmental pollution, particularly air pollution, is a subject of great scientific and public interests. The reason is due to the strong impact on human health. Air pollution is due to the placing in ...
Study of the mechanism of action of bioactive plants tarpenoids
(Universita degli studi di Salerno, 2016-05-06)
Natural products are small-molecule secondary metabolites displaying considerable structural complexity and “privileged scaffolds”. They are able to bind several endogenous targets eliciting biological effects as chemical ...
Biomolecular and biophysical approaches to interrogate epigenetic targets: a platform for drug discovery
(Universita degli studi di Salerno, 2016-04-20)
The term epigenetics refers to heritable changes in gene expression that do not involve changes in the DNA sequence. A large number of enzymes, which act mainly on histone tails and DNA, carries out epigenetic modifications, ...
Integrated metabolomics approaches for berry fruit used in nutraceutical formulations
(Universita degli studi di Salerno, 2016-04-13)
The species under investigation during these three years of PhD course were: Fragaria ananassa, Fragaria vesca, Morus alba, Morus nigra and Myrtus communis. All these species are characterized by the production of small ...
Transcriptional regulation of biosynthetic genes of the plant MEP-derived pathway to boost the metabolic flux towards bioactive diterpenes
(Universita degli studi di Salerno, 2016-02-02)
This project was aimed at enhancing the synthesis of tri-cyclic bioactive abietane diterpenes (e.g. aethiopinone, 1-oxoaethiopinone, salvipisone, and ferruginol), synthesized in the roots of Salvia sclarea and other Salvia ...
BAG3 extracellulare: target cellulari e molecolari
(Universita degli studi di Salerno, 2016-07-12)
Bcl-2-associated athanogene 3 (BAG3) belongs to the family of co-chaperone proteins that interact with the heat shock protein 70 (Hsp70) and is involved in a number of cellular processes including proliferation and apoptosis. ...