• Molecular basis of cardiomiopathy 

      Pecoraro, Michela (Universita degli studi di Salerno, 2018-04-05)
      The normal heart rhythm is guaranteed by an important intercellular junctions system, named Gap Junction (GJs). Each GJs consists of two units called connexons formed by six specific trans-membrane proteins named connexins ...
    • Neurodegeneration in Chronic Kidney Disease: role of neuroinflammation and uremic toxins 

      Adesso, Simona (Universita degli studi di Salerno, 2017-03-28)
      Neuroinflammation and oxidative stress have been recognized as common aspects in neurodegenerative diseases. Although the inflammatory process may induce beneficial effects, such as the elimination of the pathogen, ...
    • Role of CD73 in patients with advanced melanoma treated with anti-PD-1 agents 

      Turiello, Roberta (Universita degli studi di Salerno, 2022-04-04)
      The treatment of metastatic melanoma was revolutionized by the approval of inhibitors of immune-checkpoints, including antibodies targeting the programmed cell death protein 1 (PD- 1), such as nivolumab and pembrolizumab. ...
    • Role of TFF1 in tumor progression 

      Romano, Elena (Universita degli studi di Salerno, 2017-03-31)
      Trefoil Factor 1 (TFF1) is a small secreted protein, belonging to the trefoil factor family, characterized by a conserved “trefoil domain” containing six cysteine residues that form a three loop disulphide structure. It ...