Translational Medicine @ UniSa. Vol.4 (sept.-dec. 2012)
INDEX
Immissioni Recenti
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To NFkB or not to NFkB: the dilemma on how to inhibit a cancer cell fate regulator
(2012)Nuclear factor B (NFB) is a transcription factor that plays an important role in carcinogenesis as well as in the regulation of inflammatory response. NFB is constitutively expressed in tumours where it induces ... -
Sisters acts: converging signaling between CaMKII and CaMKIV, two members of the same family
(2012)Calcium (Ca2+ ) is a universal second messenger that regulates a number of diverse cellular processes including cell proliferation, development, motility, secretion, learning and memory1, 2. A variety of stimuli, ... -
Minimally invasive swine experimental model for the in vivo study of liver metabolism of drugs
(2012)Purpose: To develop a clinically relevant porcine model for the study of hepatic metabolism of drugs by means of hepatic vein catheterization. Materials and Methods: review of literature and elaboration of a hypothesis, ... -
Pediatric health mobility: is it only an italian problem?
(2012)Intra-regional, extra-regional and international health mobility are important phenomena for regional and national healthcare planning. Pediatric data on this topic are scarce. We therefore conducted a systematic ... -
Environmental pollution effectson reproductive health? Clinical-epidemiological study in southern Italy
(2012)This study aims to address the clinical, statistical and Epidemiological Relationship Between Birth Defects and Environmental Pollution, in the Campania Region and in Salerno. Objectives: We examined four groups of subjects ... -
Transculturality: the new frontier of care relationships
(2012)Taking care of migrants constitutes a new challenge for the actual operative structures of the services in general and for the sanitary service in particular, requiring a global and permanent rethinking with regards ... -
Dopamine use in intensive care: are we ready to turn it down?
(2012)Dopamine is still frequently used as a first line vasopressor agent in hypotensive patients, when physicians are afraid of noradrenaline and believe that dopamine, with its β and α, inotrope and vasopressor effects, ... -
A new long-term reversible contraception method: sexual and metabolic impact
(2012)Background: data relating to the influence of hormonal contraception on sexual life are conflicting and mostly they refer to oral contraceptives. In this study we evalueted the effect of a long-acting contraceptive on ... -
An engineering approach to biomedical sciences: advanced testing methods and pharmacokinetic modeling
(2012)In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical ... -
Allergens in allergy diagnosis: a glimpse at emerging new concepts and methodologies
(2012)Allergic diseases are important concern of public health. A reliable diagnosis is of utmost importance for the management of allergic patients both when immunotherapy is planned and when the treatment is essentially based ... -
1,4-Dihydropyridines: the multiple personalities of a blockbuster drug family
(2012)More than 40 years after their introduction in therapy, 1,4-dihydropyridines (DHPs) are still amongst the most prescribed drugs in the world. Though they all share a similar mechanism of action blocking L-type voltage-gated ... -
An engineering approach to biomedical sciences: advanced strategies in drug delivery systems production
(2012)Development and optimization of novel production techniques for drug delivery systems are fundamental steps in the “from the bench to the bedside” process which is the base of translational medicine. In particular, in the ...
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