Sfoglia Drug Discovery & Development per Soggetto "BIO/14 FARMACOLOGIA"

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    • Is the inflammasome at the crosstalk between COPD and lung cancer? 

      Colarusso, Chiara (Universita degli studi di Salerno, 2020-10-26)
      Background. Chronic obstructive pulmonary disease (COPD) is considered as a risk factor for lung cancer establishment. Epidemiological evidence indicate that patients with COPD have a 6.35-fold higher risk to develop lung ...

    • Role of CD73 - A2A/A2B receptors axis in cancer 

      Sorrentino, Claudia (Universita degli studi di Salerno, 2018-04-05)
      The adenosinergic pathway plays a critical role in cancer development and progression, as well as in drug resistance to chemotherapy and/or targeted-therapy. The goal of this PhD thesis was to investigate and fully ...

    • The Winnie-APCmin as an innovative tool to investigate the axis between inflammation and colorectal cancer 

      Chieppa, Marcello (Universita degli studi di Salerno, 2019-05-07)
      During these last three yeas of PhD we aimed to create a new murine model of spontaneous inflammatory-induced colorectal cancer a combining the genetic susceptibility of the APCMin model and the chronic intestinal inflammation ...