Now showing items 161-162 of 162

    • Chemical proteomics on ligand protein 

      Margarucci, Luigi (Universita degli studi di Salerno, 2011-03-18)
      The emerging field of mass spectrometry-based chemical proteomics provides a powerful instrument in the target discovery of bioactive small-molecules, such as drugs or natural products[1]. The identification of their ...
    • Design and synthesis of new polycyclic compounds with potential anticancer activity 

      Musella, Simona (Universita degli studi di Salerno, 2011-02-21)
      p53 is best known as a tumor suppressor that transcriptionally regulates, in response to cellular stresses such as DNA damage or oncogene activation, the expression of various target genes that mediate cell-cycle arrest, ...