Please use this identifier to cite or link to this item: http://elea.unisa.it:8080/xmlui/handle/10556/1648
Title: Is 2-deoxy-2-[18F]fluoro-D-glucose PET/CT acquisition from the upper thigh to the vertex of skull useful in oncological patients?
Authors: Salvatore, Barbara
Caprio, Maria Grazia
Fonti, Rosa
D’Amico, D.
Fraioli, F.
Salvatore, Marco
Pace, Leonardo
Keywords: PET/CT
Whole-body acquisition
Head
Brain
Issue Date: 2015
Citation: Salvatore B, Caprio MG, Fonti R, D’Amico D, Fraioli F, Salvatore M, Pace L. Is 2-deoxy-2-[18F]fluoro-D-glucose PET/CT acquisition from the upper thigh to the vertex of skull useful in oncological patients? Translational Medicine @ UniSa 2015, 11(6):34-38
Abstract: Aim: To assess whether performing routinely 2-deoxy-2- [18F]fluoro-D-glucose PET/CT (18FDG PET/CT) scan from the upper thigh to the vertex of skull is clinically relevant. Materials and Methods: 3502 (1634 female; mean-age 60+16) consecutive patients undergoing 18FDG PET/CT were retrospectively analyzed. Patients were divided in 10 groups according to primary malignancy. Chi-square analysis was used to assess differences among proportions. A p value < 0.05 was considered significant. Results: 18FDG PET/CT was positive in head district in 130/3502 (3,7%) patients. In all patients lesions were unknown before PET/CT examination. PET/CT showed 158 positive brain/head uptake in the 130 patients. The 158 lesions were localized in: brain (43/158; 27%), bone (52/158; 33%), lymph node (1/158; 0,6%), soft tissue (55/158; 35%) and other sites (7/158; 4,4%). According to each group, patients were positive in the head district in 1.0% for Gastrointestinal Cancer (7/690), 3.0 % for Genitourinary Cancer (3/101), 3.7 % for Haemathologic Cancer (59/1590), 2.7 % for Gynaecologic Cancer (3/112), 7.8% for Head-Neck-Thyroid and Parathyroid Cancer (26/331), 3.5% for Breast Cancer (7/200), 2.6% for Lung Cancer (7/271), 3.4% for Melanoma (2/59), 7.4% for Sarcoma (2/27), 11.6% for Unknown Primary Tumour (14/121). Conclusion: Our data show a relatively high incidence of brain/head lesion in patients with Unknown Primary Tumour.
URI: http://hdl.handle.net/10556/1648
http://dx.doi.org/10.14273/unisa-452
ISSN: 2239-9747
Appears in Collections:Translational Medicine @ UniSa. Volume 11 (jan.-apr. 2015)



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