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dc.contributor.authorCaprio, Maria Grazia-
dc.contributor.authorCapacchione, Daniela-
dc.contributor.authorMainolfi, Ciro-
dc.contributor.authorSpera, Anna Maria-
dc.contributor.authorSalvatore, Barbara-
dc.contributor.authorCella, Laura-
dc.contributor.authorSalvatore, Marco-
dc.contributor.authorPace, Leonardo-
dc.date.accessioned2013-04-10T10:20:43Z-
dc.date.available2013-04-10T10:20:43Z-
dc.date.issued2012-
dc.identifier.citationCaprio MG, Capacchione D, Mainolfi C, et al. 18F-FDG PET and PET/CT in the localization and characterization of lesions in patients with ovarian cancer. Translational Medicine @ UniSa 2012;2(4):28-35en_US
dc.identifier.issn2239-9747en_US
dc.identifier.urihttp://hdl.handle.net/10556/531-
dc.description.abstractAim: The aim was to compare the imaging findings of 18F-fluorodeoxyglucose (18F-FDG) PET and integrated PET/CT in patients with primary, recurrent or metastatic ovarian cancer. Materials and methods. 21 women with ovarian cancer were evaluated. All patients had a integrated PET/CT scan. Localization, infiltration and uptake intensity of [18F]FDG were evaluated on PET and PET/CT. The certainty of localisation and characterisation was scored on a 3 point scale (L1 definite localisation; L2 probable localisation; L3 uncertain localisation; C1 benign; C2 equivocal; C3 malignant). Results. PET scored as L1 54 lesions (44%), as L2 51 (42%), and as L3 17 (14%). On the other hand, PET/CT scored as L1 120 lesions (98%), as L2 2 (2%), and none as L3. Thus PET/CT allowed a better localization in 54% of lesions. Moreover, PET scored as C1 25 lesions (20%), as C2 62 (51%), and as C3 35 (29%) . On the other hand, PET/CT scored as C1 57 lesions (47%), as C2 13 (11%), and as C3 52 (42%). Thus PET/CT allowed a sensible reduction in the number of equivocal lesions (40%). Even when patients were subgrouped on the basis of clinical stage of the disease, PET/CT was capable of better definition of the lesions either for localization and for characterization. Conclusions. In patients with ovarian cancer, PET/CT allows better anatomical localisation of pathologic uptake providing high accuracy for staging and restaging of ovarian cancer when compared with PET alone.en_US
dc.format.extentP. 28-35en_US
dc.language.isoenen_US
dc.sourceUniSa. Sistema Bibliotecario di Ateneoen_US
dc.subjectOvarian canceren_US
dc.subject18F-FDGen_US
dc.subjectPET/CTen_US
dc.title18F-FDG PET and PET/CT in the localization and characterization of lesions in patients with ovarian canceren_US
dc.typeArticleen_US
È visualizzato nelle collezioni:Translational Medicine @ UniSa. Vol.2 (jan.-apr. 2012)



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