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Accelerated bone mass senescence after hematopoietic stem cell transplantation 

Serio, Bianca; Pezzullo, Luca; Fontana, Raffaele; Annunziata, Silvana; Rosamilio, Rosa; Sessa, M.; Giudice, Valentina; Ferrara, Ida Lucia; Rocco, Monia; De Rosa, Gennaro; Ricci, P.; Tauchmanovà, Libuse; Montuori, Nunzia; Selleri, Carmine (2013)
Osteoporosis and avascular necrosis (AVN) are long-lasting and debilitating complications of hematopoietic stem cell transplantation (HSCT). We describe the magnitude of bone loss, AVN and impairment in osteogenic cell ...
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Clonal non-malignant hematological disorders: unraveling molecular pathogenic mechanisms to develop novel targeted therapeutics 

Risitano, Antonio M.; Selleri, Carmine (2014)
Clonal non-malignant hematological disorders are a heterogeneous group of diseases that are particularly challenging for hematologists. Indeed, most obvious and frequent hematological diseases include a broad spectrum of ...
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OPSI threat in hematological patients 

Serio, Bianca; Pezzullo, Luca; Giudice, Valentina; Fontana, Raffaele; Annunziata, Silvana; Ferrara, Ida Lucia; Rosamilio, Rosa; De Luca, C.; Rocco, Monia; Montuori, Nunzia; Selleri, Carmine (2013)
Overwhelming post-splenectomy infection (OPSI) is a rare medical emergency, mainly caused by encapsulated bacteria, shortly progressing from a mild flu-like syndrome to a fulminant, potentially fatal, sepsis. The risk of ...
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Immunological derangement in Hypocellular Myelodysplastic Syndromes 

Serio, Bianca; Risitano, Antonio M.; Giudice, Valentina; Montuori, Nunzia; Selleri, Carmine (2014)
Hypocellular or hypoplastic myelodysplastic syndromes (HMDS) are a distinct subgroup accounting for 10–15% of all MDS patients, that are characterized by the presence of bone marrow (BM) hypocellularity, various degree of ...
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Molecular Pathogenesis of Myelodysplastic Syndromes 

Visconte, Valeria; Selleri, Carmine; Maciejewski, Jaroslaw P.; Tiu, Ramon V. (2014)
Myelodysplastic syndromes (MDS) are a group of clonal hematologic disorders characterized by inefficient hematopoiesis, hypercellular bone marrow, dysplasia of blood cells and cytopenias. Most patients are diagnosed in ...
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In vitro apoptotic effects of farnesyltransferase blockade in acute myeloid leukemia cells 

Giudice, Valentina; Ricci, Pier Carlo; Marino, Luigi; Rocco, Mattia; Villani, Gaetano; Langella, Monica; Manente, Lisa; Seneca, Elisa; Ferrara, Idalucia; Pezzullo, Luca; Serio, Bianca; Selleri, Carmine (2016)
Farnesyltransferase inhibitors (FTIs) are a class of oral anti-cancer drugs currently tested in phase I-II clinical trials for treatment of hematological malignancies. The in vitro effects of various FTIs (alpha-hydroxyf ...
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67 kDa laminin receptor (67LR) in normal and neoplastic hematopoietic cells: is its targeting a feasible approach? 

Montuori, Nunzia; Pesapane, Ada; Giudice, Valentina; Serio, Bianca; Rossi, Francesca Wanda; De Paulis, Amato; Selleri, Carmine (2016)
The 67 kDa laminin receptor (67LR) is a non-integrin cell surface receptor for laminin (LM) that derives from a 37 kDa precursor (37LRP). 67LR expression is increased in neoplastic cells and correlates with an enhanced ...
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Urokinase type plasminogen activator receptor (uPAR) as a new therapeutic target in cancer 

Montuori, Nunzia; Pesapane, Ada; Rossi, Francesca Wanda; Giudice, Valentina; De Paulis, Amato; Selleri, Carmine; Ragno, Pia (2016)
The urokinase (uPA)-type plasminogen activator receptor (uPAR) is a GPIanchored receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. uPAR also regulates cell adhesion, migration and proliferati ...
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Prolonged complete hematologic response in relapsed/refractory T-large granular lymphocyte leukemia after bendamustine treatment 

Rosamilio, Rosa; Giudice, Valentina; Ferrara, Idalucia; Annunziata, Silvana; Pezzullo, Luciano; Villani, Gaetano; Baldi, Carlo Eugenio; Guariglia, Roberto; Rocco, Mattia; Selleri, Carmine (2016)
T-large granular lymphocyte leukemia (T-LGLL) is a chronic clonal proliferation of effector memory cytotoxic CD3+CD57+CD56- T cells and the current guidelines suggest immunosuppressive therapy as first-line therapy, but the ...
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The urokinase/urokinase receptor system in mast cells: effects of its functional interaction with fmlf receptors 

Rossi, Francesca Wanda; Prevete, Nella; Rivellese, Felice; Napolitano, Filomena; Montuori, Nunzia; Postiglione, Loredana; Selleri, Carmine; De Paulis, Amato (2016)
Mast cell and basophils express the high affinity receptor for IgE (FcRI) and are primary effector cells of allergic disorders. The urokinase (uPA)-mediated plasminogen activation system is involved in physiological and ...
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Mean reticolocyte hemoglobin content index plays a key role to identify children who are carriers of β –thalassemia 

Vicinanza, Paolo; Vicinanza, Mariella; Cosimato, Vincenzo; Terracciano, Daniela; Cancellario, Sergio; Massari, Angelo; Danise, Paolo; Selleri, Carmine; Serio, Bianca (2017)
Reticulocyte (r) and red blood cell (RBC) indices provide reliable parameters for screening and monitoring iron deficiency anemia (IDA) patients and β-thalassemia trait (BTT) carriers. The aim of this study is to identify ...
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Selleri, Carmine (11)
Giudice, Valentina (7)Montuori, Nunzia (6)Serio, Bianca (6)Annunziata, Silvana (3)De Paulis, Amato (3)Pezzullo, Luca (3)Rosamilio, Rosa (3)Rossi, Francesca Wanda (3)Ferrara, Ida Lucia (2)... View MoreSoggettoMDS (2)Acute myeloid leukemia (1)Amininreceptor (1)Apoptosis (1)Bendamustine (1)Bisphosphonates (1)Bone marrow microenvironment (1)Chemotherapy (1)Chronic T and NK disorders of granular lymphocytes (1)Clonal non-malignant hematological disorders (1)... View MoreDate Issued2016 (5)2014 (3)2013 (2)2017 (1)Has File(s)Yes (11)
EleA themes by Ugsiba