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Synthesis and properties of linear and cyclic peptoids
(2012-03-26)
Le strutture e le attività metaboliche di tutte le cellule si basano su una vasta gamma di molecole comprendenti: amminoacidi, carboidrati, lipidi e nucleotidi, insieme alle forme polimeriche di questi composti. Ognuna di ...
Design, virtual screening and structural studies of new molecules with potential antitumor and antiinflammatory activity
(2012-03-30)
Computational methodologies in combination with experimental techniques as Nuclear Magnetic Resonance (NMR) have become a crucial component in drug discovery process, from hit identification to lead optimization.
The study ...
Total synthesis of terpenoidic unsatured dialdehydes and evaluation of their activity towards TRP receptors
(2012-02-02)
The aim of this PhD project has been to develop new synthetic strategies in
enantioselective preparation of natural products.
In particular my attention has been focused on preparation of some natural
metabolite, containing ...