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Design and synthesis of “small molecules” as antiviral and radiotracer agents
(Universita degli studi di Salerno, 2011-03-28)
The present Ph.D. project was divided into different work parts, in a way that helps to understand and define the goals of this project. In particular: I) Design, synthesis and evaluation of antiviral activity of Arbidol ...
Design, synthesis and biological evaluation of new small molecule modulators of Arginine methyltransferases
(Universita degli studi di Salerno, 2011-02-21)
The methylation of arginine residues is a prevalent post-translational modification, found on both nuclear and cytoplasmic proteins, catalyzed by the protein arginine N-methyltransferase (PRMT) family of enzymes. To date ...