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Design, synthesis and biological evaluation of new small-molecule modulators of proein lysine methyltransferases (PKMTs) 

Rescigno, Donatella (Universita degli studi di Salerno, 2018-04-20)
Histone lysine methyltransferases have crucial roles in a number of biological processes and human diseases by controlling gene expression and chromatin state. Within this family, the lysine methyltransferase G9a has emerged ...
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Drug delivery to the lung in Cystic Fibrosis: deposition, dissolution, mucus interaction and microbiological evaluation of dry powder inhalers 

Manniello, Michele Dario (Universita degli studi di Salerno, 2018-04-05)
The inhalation therapy consists of a direct administration of drugs for the treatment of lung diseases. A formulation for inhalation is a valid option in the symptomatic management of pulmonary diseases typical of cystic ...
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Molecular basis of cardiomiopathy 

Pecoraro, Michela (Universita degli studi di Salerno, 2018-04-05)
The normal heart rhythm is guaranteed by an important intercellular junctions system, named Gap Junction (GJs). Each GJs consists of two units called connexons formed by six specific trans-membrane proteins named connexins ...
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Computational design of new antimicrobial peptides 

Parisi, Rosaura (Universita degli studi di Salerno, 2018-04-13)
Antimicrobial peptides (AMP) are evolutionarily conserved components of the innate immune system. They have a broad spectrum of action against bacteria, fungi and viruses. Therefore, AMP are studied as probable substitutes ...
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Design, synthesis and biological activity of new target selective antitumoral agents 

Russo, Alessandra (Universita degli studi di Salerno, 2018-04-05)
Cancer development is a complex pathological process that exploits a variety of biological actors. The identification of new molecular entities able to interfere with new biological targets, involved in tumorigenesis, is ...
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AuthorManniello, Michele Dario (1)Parisi, Rosaura (1)Pecoraro, Michela (1)Rescigno, Donatella (1)Russo, Alessandra (1)SubjectAntibiotic (1)Antimicrobial (1)Antitumoral (1)BAG3 (1)BIO/14 FARMACOLOGIA (1)Cardiotoxicity (1)CHIM/03 CHIMICA GENERALE E INORGANICA (1)CHIM/06 CHIMICA ORGANICA (1)CHIM/08 CHIMICA FARMACEUTICA (1)CHIM/09 FARMACEUTICO TECNOLOGICO APPLICATIVO (1)... View MoreDate Issued
2018 (5)
Has File(s)Yes (5)
EleA themes by Ugsiba