Lysine acetylation of histone tails is an epigenetic hallmark that plays a crucial role in the regulation of chromatin structure. Alteration in acetylation levels and/or aberrant activity in proteins involved in this crucial ...

The consumption of dietary supplements and botanicals is not always safe and free of potential health risks. In recent years, cases of contamination with hepatotoxic pyrrolizidine alkaloids, a group of plant secondary ...

My PhD research plan relates to the exploration of the structural requirements for the modulation of enzymes involved in the pathogenesis of viral infections and inflammatory disorders. The first part of my doctoral project ...

This research aimed to chemical-biological study of plant and fungal species from inland areas of Campania Region, typically used in preparations for medicinal purposes or food traditional recipes. In the preliminary part ...

The identification of natural products and synthetic compounds target proteins is pivotal to understand their mechanism of action for the development of molecular probes and/or potential drugs. Functional proteomics is a ...

Helicobacter pylori is one of the most important pathogenic bacteria associated with various gastric diseases, including cancer. This pathogen induces an acute mucosal inflammatory response and, if not eradicated, it could ...

Phytocannabinoids, the major secondary metabolites of cannabis plants, exert a wide range of biological activities. The present work was focused on investigating the mechanism of action of cannabidiolic acid (CBDA) in U87MG ...