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Development of novel anticancer compounds directed towards promising therapeutic targets 

Pierri, Martina (2023-04-19)
Lysine acetylation of histone tails is an epigenetic hallmark that plays a crucial role in the regulation of chromatin structure. Alteration in acetylation levels and/or aberrant activity in proteins involved in this crucial ...
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Targeted and untargeted proteomic approaches to disclose small molecules interactome 

Ferraro, Giusy (2023-04-24)
The identification of natural products and synthetic compounds target proteins is pivotal to understand their mechanism of action for the development of molecular probes and/or potential drugs. Functional proteomics is a ...
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Interactome analysis of bioactive molecules: optimization of a functional proteomics platform 

Morretta, Elva (2020-10-24)
The identification of natural products (NPs) target proteins is pivotal to understand their mechanism of action, in order to develop molecular probes and/or potential drugs. In the last 15 years, affinity chromatography-coupled ...
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Design, synthesis and biological activity of new target selective antitumoral agents 

Russo, Alessandra (2018-04-05)
Cancer development is a complex pathological process that exploits a variety of biological actors. The identification of new molecular entities able to interfere with new biological targets, involved in tumorigenesis, is ...
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Design and synthesis of molecules with anti-inflammatory and/or anti-cancer activit 

Colarusso, Ester (2022)
Nell'ultimo decennio, il legame tra infiammazione e cancro è risultato sempre più evidente; di conseguenza, l'identificazione di nuove molecole in grado di interferire con i targets biologici chiave coinvolti in queste ...
EleA themes by Ugsiba
 

 

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AuthorColarusso, Ester (1)Ferraro, Giusy (1)Morretta, Elva (1)Pierri, Martina (1)Russo, Alessandra (1)Subject
CHIM/06 CHIMICA ORGANICA (5)
Anticancer (1)Antitumoral (1)BAG3 (1)BRD9 (1)Bromodomain-containing protein 9 (BRD9) (1)Epigenetic (1)Infiammazione (1)Macrodomains (1)Mass spectrometry (1)... View MoreDate Issued2023 (2)2018 (1)2020 (1)2022 (1)Has File(s)Yes (5)
EleA themes by Ugsiba