Metabolomics and metabonomics encompass the comprehensive profiling of multiple metabolite concentrations and their cellular and systemic fluctuations in response to drugs, diet, lifestyle, environment, stimuli and genetic ...

Recently, considerable attention has been devoted to developing superhydrophobic surfaces due to their advantageous antimicrobial and self-cleaning properties. While significant effort has been devoted to their fabrication, ...

Phytocannabinoids, the major secondary metabolites of cannabis plants, exert a wide range of biological activities. The present work was focused on investigating the mechanism of action of cannabidiolic acid (CBDA) in U87MG ...

Lysine acetylation of histone tails is an epigenetic hallmark that plays a crucial role in the regulation of chromatin structure. Alteration in acetylation levels and/or aberrant activity in proteins involved in this crucial ...

This research aimed to chemical-biological study of plant and fungal species from inland areas of Campania Region, typically used in preparations for medicinal purposes or food traditional recipes. In the preliminary part ...

The consumption of dietary supplements and botanicals is not always safe and free of potential health risks. In recent years, cases of contamination with hepatotoxic pyrrolizidine alkaloids, a group of plant secondary ...

Main target of this PhD project was to define the metabolome of the main by-products, and in certain cases of the edible parts, of selected agroalimentary productions, that are the flowers of Opuntia ficus indica Mill. ...

Helicobacter pylori is one of the most important pathogenic bacteria associated with various gastric diseases, including cancer. This pathogen induces an acute mucosal inflammatory response and, if not eradicated, it could ...

Focusing the attention on the futuristic concept of personalized medicine, the Ph.D. project aimed to demonstrate the potentialities of hydrogels as a versatile feed material for the semi solid extrusion 3D printing process ...

The identification of natural products and synthetic compounds target proteins is pivotal to understand their mechanism of action for the development of molecular probes and/or potential drugs. Functional proteomics is a ...