Sfoglia Translational Medicine @ UniSa per Titolo
Items 28-47 di 284
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Biology of Immunoglobulins
(2015)Intravenous Immunoglobulins (IvIg) are often administered to critically ill patients more as an act of faith than on the basis of relevant clinical studies. This particularly applies to the treatment of sepsis in ... -
Bivalirudin in patients undergoing pci: state of art and future perspectives
(2016)Acute coronary syndrome (ACS) represents the most common cause of death worldwide. Percutaneous coronary intervention (PCI) is the management of choice in patients with ACS and occurrence of intra procedural thrombotic ... -
Breakthrough pain: the importance of baseline analgesic regimen with opioids
(2012)Pain is one of the most common and often most feared symptoms in patients with cancer. Ongoing or progressive pain is physically debilitating and has a marked impact on quality of life. During their illness, at least ... -
Care for carers: an investigation on family caregivers' needs, tasks, and experiences
(2019)Family caregivers have an essential active role in cancer patients assistance at home. They play a key role in the management of patients and provide some caregiving activities once provided only by professional ... -
Carotid and vagal body paragangliomas
(2013)Between 1972 and 2012, 25 patients presenting 32 paragangliomas of the neck were observed. Tumor locations included the carotid body (CBTs) in 21 patients and the vagus nerve in 4. Four patients had bilateral CBT and one ... -
Clinical and radiographic mid-term outcomes after total shoulder replacement: a retrospective study protocol including 400 anatomical and reverse prosthetic implants
(2016)Objectives: To obtain outcomes data on anatomical and reverse total shoulder arthroplasty by analysis of clinical scores and standard radiographs. Subject selection and enrollment: 400 consecutive series of patients replaced ... -
The clinical significance of delirium in the intensive care unit
(2012)Delirium is prevalent among intensive care unit patients. It prolongs length of stay, increases costs, and is independently associated with higher mortality rates. While its specific biological pathways are largely unknown, ... -
Clonal non-malignant hematological disorders: unraveling molecular pathogenic mechanisms to develop novel targeted therapeutics
(2014)Clonal non-malignant hematological disorders are a heterogeneous group of diseases that are particularly challenging for hematologists. Indeed, most obvious and frequent hematological diseases include a broad spectrum of ... -
Cognitive stimulation in older adults: an innovative good practice supporting successful aging and self-care
(2019)The project Cognitive Stimulation in Older Adults: Intervention on Cognitive Frailty and Promotion of Self-Care (in brief the ECOG project) arises in a context of worldwide demographic aging, and is fostered by the ... -
Combined Administration of Oxycodone/Naloxone in Chronic Osteo-Articular Diseases Pain Therapy
(2014)The aim of this study is the analysis of the beneficial impact of using opioid receptor antagonist associated to opioid analgesic on the quality of life in patients suffering from chronic non-cancer pain. We recruited 60 ... -
Complementary Therapy in Polycystic Ovary Syndrome
(2014)Polycystic Ovary Syndrome (PCOS) is an endocrine disease. PCOS afflicts 5 to 10 % of women of reproductive age. The symptoms are: amenorrhea, oligomenorrhea, hirsutism, obesity, infertility, chronic hyperandrogenic anovulation ... -
Complications of the “nuss procedure” in pectus excavatum
(2020)During the pediatric age range, one the most frequent deformities of the chest wall are Pectus Excavatum (PE). Currently the treatment of choice for PE is surgical intervention following the Nuss procedure. In this ... -
Congenital cystic adenomatoid malformation of the lung tipe II: three cases report
(2019)Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung lesion. It may appear since birth (30-35%) with difficulty breathing or may have a late onset (60- 65%) with recurring pulmonary infections ... -
Current Concepts on Diagnosis and Treatment of Mastocytosis
(2014)Mastocytosis is a heterogeneous group of disorders characterized by a clonal proliferation and accumulation of mast cells in one or more organ, primarily in the skin and bone marrow. The clinical spectrum of the disease ... -
Current ESPGHAN guidelines for celiac disease in pediatric age, tertiary care center experience: a proposal for further simplification
(2019)According to the 2012 ESPGHAN criteria for diagnosis of celiac disease (CD), duodenal biopsy (DB) can be avoided in children with a clear malabsorption syndrome, anti-tissue transglutaminase IgA (tTG2) ≥ 10x the cut-off, ... -
Designing in-vitro systems to simulate the in-vivo permeability of drugs
(2014)In this work an engineering approach, consisting in an experimental procedure and a model to derive the data, was presented and applied to improve the testing methods of pharmaceuticals. The permeability of several ... -
The determinants of translational medicine success - A managerial contribution
(2013)Scope of Translational Medicine is to speed the development of new compounds of medical protocols and/or treatments to improve patient’s quality of life. Translational medicine represents the synergy between epidemiology, ...