Browsing Translational Medicine @ UniSa by Title
Now showing items 46-65 of 284
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Designing in-vitro systems to simulate the in-vivo permeability of drugs
(2014)In this work an engineering approach, consisting in an experimental procedure and a model to derive the data, was presented and applied to improve the testing methods of pharmaceuticals. The permeability of several ... -
The determinants of translational medicine success - A managerial contribution
(2013)Scope of Translational Medicine is to speed the development of new compounds of medical protocols and/or treatments to improve patient’s quality of life. Translational medicine represents the synergy between epidemiology, ... -
Dexmedetomidine: current role in burn ICU
(2017)Dexmedetomidine (DEX) is a relatively recent a2-adrenergic agonist which provides sedation, anxiolysis and analgesia with much less respiratory depression than other sedatives. These characteristics have implemented the ... -
Dietary restriction for the treatment of Meniere’s disease
(2020)Meniere's disease (MD) is an idiopathic inner ear disorder characterized by spontaneous recurrent vertigo, fluctuating sensorineural hearing loss (SNHL), aural fullness and tinnitus. Endolymphatic hydrops (EH) of the ... -
Digital innovation in healthcare: a device with a method for monitoring, managing and preventing the risk of chronic polypathological patients
(2020)New digital technologies can have a huge impact on the traditional healthcare sector, both from a clinical and economic perspective. Doctors and health specialists will increasingly need technology to improve the ... -
Digital services landscape in primary care setting in city of Zagreb; an EIP-AHA reference site case study
(2019)European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) brings together partners to create innovative solutions to the challenges of aging. Reference Sites (RS) of the Partnership act as hubs of ... -
Discovering the meaning of monoclonal gammopathy of undetermined significance: current knowledge, future challenges
(2014)Monoclonal gammopathy of undetermined significance (MGUS) is a non malignant plasma cell disorder with a relatively low risk of progression to Multiple Myeloma (MM) and to related Plasma cells disordes (lymphoplasmacellular ... -
Dopamine use in intensive care: are we ready to turn it down?
(2012)Dopamine is still frequently used as a first line vasopressor agent in hypotensive patients, when physicians are afraid of noradrenaline and believe that dopamine, with its β and α, inotrope and vasopressor effects, ... -
. Double-microcatheter technique through tortuous anatomy for coil embolization of a saccular splenic aneurysm: a technical report
(2020)We report on a case of an asymptomatic splenic artery aneurysm (SAA) with a large neck in a 53-year-old female with an extreme vessel tortuosity which was treated with a Double Microcatheter Technique. This endovascular ... -
Drug-induced Sleep Endoscopy (DISE) with Simulation Bite to Predict the Success of Oral Appliance Therapy in Treating Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
(2020)Study objectives: Oral appliances have gained their place in the treatment of obstructive sleep apnea (OSA) where custom-made titratable mandibular advancement devices (MAD) have become the oral appliance of choice. ... -
Dual role of grk5 in cancer development and progression
(2016)GRK5 is a multifunctional protein that is able to move within the cell in response to various stimuli to regulate key intracellular signaling from receptor activation, on plasmamembrane, to gene transcription, in the ... -
Early Surgery after Coronary Revascularization: A Fine Line between Bleeding and Thrombosis
(2015)Management of PCI patients undergoing early surgery is still a matter of debate. Noteworthy, PCI patients require a dual antiplatelet therapy (DAPT), with aspirine and a thienopiridine (clopidogrel, prasugrel, ticagrelor), ... -
Eating and Nutrition Habits in Young Competitive Athletes: A Comparison between Soccer Players and Cyclists
(2015)The study evaluated the dietary habits in two groups of young athletes, practicing two different sports: soccer players and cycling. The dietary habits of 47 athletes were investigated by questionnaire. Body Mass Index, ... -
Economic evaluation of “pulse dose” radiofrequency in the treatment of occipital neuralgia headache
(2012)Headache occipital neuralgia is an example of pain-disease for which treatment both pharmacological protocols and invasive methods are used. Among the latter, the RF (Radiofrequency) pulse-dose has been of interest for the ... -
Effect of Backward Walking on Attention: Possible Application on ADHD
(2015)The human requires attentive effort as assessed in dual-task experiments. Consistently, an attentive task can modify the walking pattern and a attention deficit and hyperactivity disorder (ADHD) is accompanied by gait ... -
Effect of α2-adrenergic agonists and antagonists on cytokine release from human lung macrophages cultured in vitro
(2016)The most trusted hypothesis to explain how α2-adrenergic agonists may preserve pulmonary functions in critically ill patients is that they directly act on macrophages by interfering with an autocrine/paracrine adrenergic ...