• Focusing on diabetic ulcers 

      Setacci, Carlo; Benevento, Domenico; De Donato, Gianmarco; Viviani, Emanuela; Bracale, Umberto Marcello; Del Guercio, Luca; Palasciano, Giancarolo; Setacci, Francesco (2020)
      Foot ulcers associated with Diabetes mellitus require immediate attention due to risk of amputation if left untreated. Herein we focus on the mitigating risk factors and physiopathology of the diabetic foot, recounting ...
    • Genetic test for dilated and hypertrophic cardiomyopathies: useful or less than useful for patients? 

      Pastore, Fabio; Parisi, Valentina; Romano, Rosalba; Rengo, Giuseppe; Pagano, Gennaro; Komici, Klara; Leosco, Dario (2013)
      Genetic testing for potentially heritable cardiomyopathies has advanced from basic scientific discovery to clinical application. Nowadays, genetic diagnostic tests for cardiomyopathies are clinically available. As ...
    • Genetic test for the channelopaties: useful or less than useful for patients? (part 2.) 

      Romano, Rosalba; Parisi, Valentina; Pastore, Fabio; Riccio, A.; Petraglia, Laura; Allocca, Elena; Leosco, Dario (2013)
      The advanced knowledge about genetic diseases and their mutations has widened the possibility to have a more precise and definitive diagnosis in many patients, but the use of genetic testing is still controversial. Actually, ...
    • Genomics DNA Profiling in Elite Professional Soccer Players: A Pilot Study 

      Kambouris, Marios; Del Buono, Angelo; Maffulli, Nicola (2014)
      Functional variants in exonic regions have been associated with development of cardiovascular disease, diabetes and cancer. Athletic performance can be considered a multi-factorial complex phenotype. Genomic DNA was extracted ...
    • Glomus Tumor of the Thenar Eminence in Neurofibromatosis Type 1: Case Report and Literature Review 

      Scaravilli, Gabriele; Rossi, Roberto; Artiaco, Stefano; Merolla, Giovanni (2015)
      Neurofibromatosis type 1 (NF1) is a disease characterized by increased tumorigenesis susceptibility, caused by mutations of the oncosuppressor gene NF1. The glomus tumor (GT) is a rare, very painful mesenchymal neoplasm, ...
    • Harmonic focus versus conventional electrocautery for femoral artery exposure: a "direct" comparison on the same patients 

      Maisto, Maria; Ferrante, Liborio; Giribono, Anna Maria; Sodo, Maurizio; Panagrosso, Marco; Peluso, Andrea; Del Guercio, Luca; Bracale, Umberto Marcello (2020)
      Surgical access complications during endovascular aneurysm repair (EVAR) are reported relatively frequent. HARMONIC FOCUS® (HF; Ethicon EndoSurgery Inc., Cincinnati, Ohio, USA) is a device developed to improve bleeding ...
    • Health tourism: an opportunity for sustainable development 

      Illario, Maddalena; De Luca, Vincenzo; Leonardini, Lisa; Kucharczyk, Maciej; Parent, Anne-Sophie; Dantas, Carina; Jegundo, Ana Luísa; Van Staalduinen, Willeke; Ganzarain, Javier; Comisso, Leopoldo; Bramezza, Carlo; Carriazo, Ana Maria; Maritati, Antonio; Tramontano, Giovanni; Capozzi, Pierfrancesco; Goossens, Eva; Cotrone, Carmela; Costantini, Arianna; Ciliberti, Michela; Femiano, Maria; D’Amore, Antonio; Forlenza, Maria; Ruggiero, Rosa; Bianchi, Attilio; Augustin, Lua; Marrazzo, Vincenzo; Dello Ioio, Tristano; Capaldo, Steven J.; Crudeli, Aurelio; De Cesare, Giovanni; Cuccaro, Fausta; Bracale, Giancarlo; Tramontano, Donatella; Postiglione, Amedeo; Matera, Camilla; Coscioni, Enrico; Bousquet, Jean (2019)
      In February 2017, the “Programma Mattone Internazionale Salute” (ProMis), that is the Italian Program for Internationalization of Regional Health Systems of the Ministry of Health (MoH), presented the first version of ...
    • Heart Failure in a Dedicated Outpatient Clinic: Results after 58 Month Follow-Up. Can it be Enough? 

      Mirra, Marco; Vitulano, Gennaro; Virtuoso, N.; Tufano, Nicola; D’Auria, Francesco; De Angelis, S.; Giudice, Roberta; Lambiase, Alessandro; Gigantino, Alberto; Piscione, Federico (2015)
      Incidence of chronic heart failure (HF) is rapidly increasing, approaching a 10 per 1000 rate after 65 years of age. In the last decades, despite pharmacological, interventional and supportive innovations, HF prognosis ...
    • High density lipoprotein cholesterol increasing therapy: the unmet cardiovascular need 

      Cimmino, Giovanni; Ciccarelli, Giovanni; Morello, Alberto; Cicarelli, Michele; Golino, Paolo (2015)
      Despite aggressive strategies are now available to reduce LDL-cholesterol, the risk of cardiovascular events in patients with coronary artery disease remains substantial. Several preclinical and clinical studies have shown ...
    • How healthy is community-dwelling elderly population? Results from southern Italy 

      Guerriero, Francesca; Orlando, Valentina; Tari, Daniele Ugo; Di Giorgio, Annalisa; Cittadini, Antonio; Trifirò, Gianluca; Menditto, Erica (2015)
      PURPOSE To explore the frequency of polypharmacy, functional and cognitive capacity among the elderly in Southern Italy. METHODS Populationbased retrospective cross-sectional study. Information were retrieved from ...
    • How to repair non-atheromatous carotid lesions 

      Bouayed, Mohamed Nadjib; Bouziane, Leila Ahlam (2020)
      Non-atheromatous surgical lesions are estimated to represent at most 10% of all carotid procedures, most of which involve atheromatous lesions. Isolated tortuosity of the carotid vessels is sometimes treated surgically. ...
    • Hydrocephalus onset after microsurgical or endovascular treatment for acute subarachnoid hemorrhage. Retrospective Italian Multicenter Study 

      Gangemi, Michelangelo; Cavallo, Luigi Maria; Di Somma, Alberto; Mazzucco, Grazia Marina; Bono, Paolo Sebastiano; Ghetti, Giovanni; Zambon, Giampaolo (2014)
      Background: Chronic shunt-dependent hydrocephalus is a complication of aneurysmal subarachnoid hemorrhage (aSAH). Its incidence and risk factors have been described while the hydrocephalus onset in terms of days after ...
    • Immunologic Changes in Frail Older Adults 

      Wang, George C.; Casolaro, Vincenzo (2014)
      Several studies have shown a heightened inflammatory state in frail older adults, marked by high serum levels of interleukin-6 and C-reactive protein and an increased number of circulating leukocytes. Activation of monocytes ...
    • Immunological derangement in Hypocellular Myelodysplastic Syndromes 

      Serio, Bianca; Risitano, Antonio M.; Giudice, Valentina; Montuori, Nunzia; Selleri, Carmine (2014)
      Hypocellular or hypoplastic myelodysplastic syndromes (HMDS) are a distinct subgroup accounting for 10–15% of all MDS patients, that are characterized by the presence of bone marrow (BM) hypocellularity, various degree of ...
    • Implementing an ict-based polypharmacy management program in Italy 

      Arcopinto, Michele; Cataldi, Mauro; De Luca, Vincenzo; Orlando, Valentina; Simeone, Giuseppe; D’Assante, Roberta; Postiglione, Alfredo; Guida, Antonella; Trama, Ugo; Illario, Maddalena; Coscioni, Enrico; Iaccarino, Guido; Cuccaro, Paula; D’Onofrio, Gaetano; Vigorito, Carlo; Cittadini, Antonio; Ferrara, Nicola; Menditto, Enrico (2017)
      Although there is evidence of a growing awareness of the problem, no official policy statements or regulatory guidelines on polypharmacy have been released up to date by Italian Health Authorities. Medication review, ...
    • In vitro apoptotic effects of farnesyltransferase blockade in acute myeloid leukemia cells 

      Giudice, Valentina; Ricci, Pier Carlo; Marino, Luigi; Rocco, Mattia; Villani, Gaetano; Langella, Monica; Manente, Lisa; Seneca, Elisa; Ferrara, Idalucia; Pezzullo, Luca; Serio, Bianca; Selleri, Carmine (2016)
      Farnesyltransferase inhibitors (FTIs) are a class of oral anti-cancer drugs currently tested in phase I-II clinical trials for treatment of hematological malignancies. The in vitro effects of various FTIs (alpha-hydr ...
    • Innovative approaches to active and healthy ageing: Campania experience to improve the adoption of innovative good practices 

      De Luca, Vincenzo; Tramontano, Giovanni; Del Giudice, Carmine; Grimaldi, Iolanda; Romano, Rosaria; Liguori, Ilaria; Carpinelli Mazzi, Michele; Di Carluccio, Nadia; Riccio, Paolo A.; Speranza, Patrizia; Iavarone, Alessandro; Abete, Pasquale; Postiglione, Amedeo; Cataldi, Mauro; Vallone, Cayetano; Giallauria, Francesco; Cittadini, Antonio; Triggiani, Maurizio; Savastano, Silvia; Menditto, Enrica; Leonardini, Lisa; Colao, Annaria; Triassi, Maria; Iaccarino, Guido; Postiglione, Amedeo; Coscioni, Enrico; Illario, Maddalena (2019)
      The demographic projections on the European population predict that people aged over 60 will increase by about two million/year in the next decades. Since 2012, the Campania Reference Site of the European Innovation ...