Sfoglia Translational Medicine @ UniSa per Autore "Lamberti, Gaetano"

Items 1-4 di 4

    • Designing in-vitro systems to simulate the in-vivo permeability of drugs 

      Cascone, Sara; Lamberti, Gaetano; Titomanlio, Giuseppe (2014)
      In this work an engineering approach, consisting in an experimental procedure and a model to derive the data, was presented and applied to improve the testing methods of pharmaceuticals. The permeability of several ...

    • An engineering approach to biomedical sciences: advanced testing methods and pharmacokinetic modeling 

      Lamberti, Gaetano; Cascone, Sara; Titomanlio, Giuseppe (2012)
      In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical ...

    • Pharmacokinetics of remifentanil: a three-compartmental modeling approach 

      Cascone, Sara; Lamberti, Gaetano; Titomanlio, Giuseppe; Piazza, Ornella (2013)
      Remifentanil is a new opioid derivative drug characterized by a fast onset and by a short time of action, since it is rapidly degraded by esterases in blood and other tissues. Its pharmacokinetic and pharmacodynamics ...

    • SiRNA delivery for control of cyclin d1 and e2f1 expression in crohn’s disease 

      Russo, Ilaria; Carrizzo, Albino; Bochicchio, Sabrina; Piazza, Ornella; Lamberti, Gaetano; Barba, Anna Angela; Vecchione, Carmine; Zeppa, Pio; Iovino, Paola; Bucci, Cristina; Santonicola, Antonella; Ciacci, Carolina (2017)
      Evidence in inflammatory bowel diseases (IBD) supports a connection between inflammation and cancer due to the alteration of the cell cycle with loss of control at the G1/S checkpoint. In this study, we analyze ...