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Models for preclinical studies in aging-related disorders: one is not for all
(2015)
Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment–effect relationships to human subjects. ...
Unique association of rare cardiovascular disease in an athlete with ventricular arrhythmias
(2015)
Ventricular arrhythmias are a leading cause of non-elegibility to competitive sport. The failure to detect a significant organic substrate in the initial stage of screening does not preclude the identification of structural ...
Exercise as Prescription Therapy: Benefits in Cancer and Hypertensive Patients
(2015)
PURPOSE Exercise therapy in patients
with metabolic chronic disease produces several
positive response. This study aims to verify the effects
of fast walking associated to a resistance exercise to
reduce cardiovascular ...
The Validity of Adding ECG to the Preparticipation Screening of Athletes. An Evidence Based Literature Review
(2015)
Objective: To review the available evidence establishing the validity of adding electrocardiogram to the preparticipation cardiac screening in athletes. Data Sources: MEDLINE and CINAHL databases were searched. Additional ...
Is 2-deoxy-2-[18F]fluoro-D-glucose PET/CT acquisition from the upper thigh to the vertex of skull useful in oncological patients?
(2015)
Aim: To assess whether performing routinely 2-deoxy-2-
[18F]fluoro-D-glucose PET/CT (18FDG PET/CT) scan
from the upper thigh to the vertex of skull is clinically
relevant.
Materials and Methods: 3502 (1634 female; ...
A Prospective Screening of HLA-B*57.01 Allelic Variant for Preventing the Hypersensivity Reaction to Abacavir: Experience from the Laboratory of Molecular Biology of the Infectious Diseases Division at the University Hospital of Salerno
(2015)
Abacavir is a nucleoside reverse transcriptase inhibitor largely used as part of the antiretroviral therapy in Human Immunodeficiency Virus (HIV)-infected patients. Some individuals (2-9%) who start an abacavir treatment ...
The tosca registry: an ongoing, observational, multicenter registry for chronic heart failure
(2015)
The ageing of the population in western countries, the continuous increase of the prevalence of chronic diseases, the frequent coexistence of several morbid conditions (comorbidity) requires health professionals and ...
A nutritional approach to the prevention of cancer: from assessment to personalized intervention
(2015)
Among lifestyle factors, nutrition is one of the most important determinants of health, and represents a pivotal element of cancer risk. Nonetheless, epidemiological evidences of the relationship between several cancers ...
The role of physical activity on the prevention of cognitive impairment
(2015)
Physical exercise is associated with reduced risk of heart disease, type II diabetes mellitus, and overall mortality. However, growing evidence shows that physical activity can also improve cognitive function and may lower ...