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Minimally invasive swine experimental model for the in vivo study of liver metabolism of drugs
(2012)
Purpose: To develop a clinically relevant
porcine model for the study of hepatic metabolism of drugs
by means of hepatic vein catheterization.
Materials and Methods: review of literature and
elaboration of a hypothesis, ...
Sisters acts: converging signaling between CaMKII and CaMKIV, two members of the same family
(2012)
Calcium (Ca2+
) is a universal second
messenger that regulates a number of diverse cellular
processes including cell proliferation, development,
motility, secretion, learning and memory1, 2. A variety of
stimuli, such ...
Pediatric health mobility: is it only an italian problem?
(2012)
Intra-regional, extra-regional and
international health mobility are important
phenomena for regional and national healthcare
planning. Pediatric data on this topic are scarce. We
therefore conducted a systematic ...
Estrogens and neuropeptides in postmenopausal women: un update
(2012)
Menopause is characterized by depletion of ovarian follicles, a reduction of ovarian hormones to castrate levels and elevated levels of serum gonadotropins from the anterior pituitary gland. Although this process has ...
Prognostic differences between VAP caused by Acinetobacter baumannii and VAP caused by other microorganisms
(2012)
Nosocomial infection, in particular pneumonia, is an important risk factor for hospital mortality and morbidity. Acinetobacter baumannii is a common multi-resistant microorganism responsible of Ventilator Associated Pneumonia ...
Economic evaluation of “pulse dose” radiofrequency in the treatment of occipital neuralgia headache
(2012)
Headache occipital neuralgia is an example of pain-disease for which treatment both pharmacological protocols and invasive methods are used. Among the latter, the RF (Radiofrequency) pulse-dose has been of interest for the ...
A polymorphism within the promoter of the dopamine receptor D1 (DRD1 -48A7G) associates with impaired kidney function in white hypertensive patients
(2012)
Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension ...
Allergens in allergy diagnosis: a glimpse at emerging new concepts and methodologies
(2012)
Allergic diseases are important concern of public health. A reliable diagnosis is of utmost importance for the management of allergic patients both when immunotherapy is planned and when the treatment is essentially based ...
Environmental pollution effectson reproductive health? Clinical-epidemiological study in southern Italy
(2012)
This study aims to address the clinical, statistical and Epidemiological Relationship Between Birth Defects and Environmental Pollution, in the Campania Region and in Salerno.
Objectives: We examined four groups of subjects ...