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Models for preclinical studies in aging-related disorders: one is not for all

Santulli, Gaetano; Borras, Consuelo; Bousquet, Jean; Calzà, Laura; Cano, Antonio; Illario, Maddalena; Franceschi, Claudio; Liotta, Giuseppe; Maggio, Marcello; Molloy, William D.; Montuori, Nunzia; O’Caoimh, Rónán; Orfila, Francesco; Rauter, Amelia P.; Santoro, Aurelia; Iaccarino, Guido (2015)

Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment–effect relationships to human subjects. ...

How healthy is community-dwelling elderly population? Results from southern Italy

Guerriero, Francesca; Orlando, Valentina; Tari, Daniele Ugo; Di Giorgio, Annalisa; Cittadini, Antonio; Trifirò, Gianluca; Menditto, Erica (2015)

PURPOSE To explore the frequency of polypharmacy, functional and cognitive capacity among the elderly in Southern Italy. METHODS Populationbased retrospective cross-sectional study. Information were retrieved from ...