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Prognostic differences between VAP caused by Acinetobacter baumannii and VAP caused by other microorganisms
(2012)
Nosocomial infection, in particular pneumonia, is an important risk factor for hospital mortality and morbidity. Acinetobacter baumannii is a common multi-resistant microorganism responsible of Ventilator Associated Pneumonia ...
Estrogens and neuropeptides in postmenopausal women: un update
(2012)
Menopause is characterized by depletion of ovarian follicles, a reduction of ovarian hormones to castrate levels and elevated levels of serum gonadotropins from the anterior pituitary gland. Although this process has ...
A polymorphism within the promoter of the dopamine receptor D1 (DRD1 -48A7G) associates with impaired kidney function in white hypertensive patients
(2012)
Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension ...
Economic evaluation of “pulse dose” radiofrequency in the treatment of occipital neuralgia headache
(2012)
Headache occipital neuralgia is an example of pain-disease for which treatment both pharmacological protocols and invasive methods are used. Among the latter, the RF (Radiofrequency) pulse-dose has been of interest for the ...
1,4-Dihydropyridines: the multiple personalities of a blockbuster drug family
(2012)
More than 40 years after their introduction in therapy, 1,4-dihydropyridines (DHPs) are still amongst the most prescribed drugs in the world. Though they all share a similar mechanism of action blocking L-type voltage-gated ...
An engineering approach to biomedical sciences: advanced strategies in drug delivery systems production
(2012)
Development and optimization of novel production techniques for drug delivery systems are fundamental steps in the “from the bench to the bedside” process which is the base of translational medicine. In particular, in the ...
Exercise training in aging and diseases
(2012)
Sedentary lifestyle along with high blood pressure,
abnormal values for blood lipids, smoking, and obesity
are recognized risk factors for cardiovascular diseases and
for many other chronic diseases, such as ...
Treatment of clavicle fractures
(2012)
Clavicle fractures are very common injuries in adults (2-5%) and children (10-15%) (1) and represent the 44-66% of all shoulder fractures (2). Despite the high frequency the choice of proper treatment is still a challenge ...
Anatomy and surgery of the endoscopic endonasal approach to the skull base
(2012)
The midline skull base is an anatomical area, which extends from the anterior limit of the anterior cranial fossa down to the anterior border of the foramen magnum. For many lesions of this area, a variety of skull base ...