| dcterms.contributor.author | Mastantuono, Teresa | |
| dcterms.contributor.author | Di Maro, Martina | |
| dcterms.contributor.author | Chiurazzi, Martina | |
| dcterms.contributor.author | Battiloro, Laura | |
| dcterms.contributor.author | Starita, Noemy | |
| dcterms.contributor.author | Nasti, Gilda | |
| dcterms.contributor.author | Lapi, Dominga | |
| dcterms.contributor.author | Iuppariello, Luigi | |
| dcterms.contributor.author | Cesarelli, Mario | |
| dcterms.contributor.author | D’Addio, Gianni | |
| dcterms.contributor.author | Colantuoni, Antonio | |
| dc.date.accessioned | 2020-05-22T13:10:08Z | |
| dc.date.available | 2020-05-22T13:10:08Z | |
| dcterms.date.issued | 2016 | |
| dcterms.identifier.citation | Mastantuono T, Di Maro M, Chiurazzi M, Battiloro L, Starita N, Nasti G, Lapi D, Iuppariello L, Cesarelli M,D’Addio G, Colantuoni A. Microvascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric diet. Translational Medicine @ UniSa 2016, 15(1): 1-7. | it_IT |
| dcterms.identifier.issn | 2239-9747 | it_IT |
| dcterms.identifier.uri | http://www.translationalmedicine.unisa.it/index | it_IT |
| dcterms.identifier.uri | http://elea.unisa.it:8080/xmlui/handle/10556/4483 | |
| dcterms.identifier.uri | http://dx.doi.org/10.14273/unisa-2681 | |
| dc.description.abstract | The present study was aimed to assess
the changes in skin microvascular blood flow (SBF)
in newly diagnosed hyperglycemic obese subjects,
administered with hypocaloric diet. Adult patients
were recruited and divided in three groups: NW
group (n=54), NG (n=54) and HG (n=54) groups
were constituted by normal weight, normoglycemic
and hyperglycemic obese subjects, respectively. SBF
was measured by laser Doppler perfusion monitoring
technique and oscillations in blood flow were
analyzed by spectral methods under baseline
conditions, at 3 and 6 months of dietary treatment.
Under resting conditions, SBF was lower in HG
group than in NG and NW ones. Moreover, all
subjects showed blood flow oscillations with several
frequency components. In particular, hyperglycemic
obese patients revealed lower spectral density in
myogenic-related component than normoglycemic
obese and normal weight ones. Moreover, postocclusive reactive hyperemia (PORH) was impaired
in hyperglycemic obese compared to normoglycemic
and normal weigh subjects. After hypocaloric diet, in
hyperglycemic obese patients there was an
improvement in SBF accompanied by recovery in
myogenic-related oscillations and arteriolar
responses during PORH. In conclusion,
hyperglycemia markedly affected peripheral
microvascular function; hypocaloric diet ameliorated
tissue blood flow. | it_IT |
| dcterms.format.extent | P. 1-7 | it_IT |
| dc.language.iso | en | it_IT |
| dcterms.source | UniSa. Sistema Bibliotecario di Ateneo | it_IT |
| dcterms.subject | Obesity | it_IT |
| dcterms.subject | Hyperglycemia | it_IT |
| dcterms.subject | Hypocaloric diet | it_IT |
| dcterms.subject | Microvascular blood flow | it_IT |
| dcterms.subject | Laser oppler perfusion monitoring | it_IT |
| dcterms.title | Microvascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric diet | it_IT |
| dcterms.type | Article | it_IT |
